HitPredict

Interactor 1: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Interactor 2: ANR50 (Q9ULJ7)
Ankyrin repeat domain-containing protein 50
Gene: ANKRD50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	32640226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1360 Hs			1 1429
+	Hs
		1091473 TNIK_HUMAN (1-1360): 0: 1245: 100.00		ANK3_HUMAN (134-866): 1.6e-144: 492: 21.41
+	Mm
		109258 TNIK_MOUSE (1-1360): 0: 1218: 96.10		ANK3_MOUSE (692-1246): 8.52e-123: 425: 23.38
+	Hs
		332460 TNIK_HUMAN (1-1360): 0: 1245: 100.00		TNKS1_HUMAN (250-869): 6.55e-114: 392: 21.18
+	Hs
		1030710 TNIK_HUMAN (1-1360): 0: 1245: 100.00		ANK2_HUMAN (252-696): 7.73e-85: 310: 20.69
+	Mm
		1013664 TNIK_MOUSE (1-1360): 0: 1218: 96.10		ANK2_MOUSE (239-696): 1.97e-84: 308: 20.34
+	Hs
		1438854 TNIK_HUMAN (1-1360): 0: 1245: 100.00		TANC2_HUMAN (354-728): 8.24e-60: 229: 22.66
+	Mm
		59042 TNIK_MOUSE (1-1360): 0: 1218: 96.10		TANC2_MOUSE (354-728): 1.18e-59: 228: 22.91
+	Hs
		274257 TNIK_HUMAN (1-1360): 0: 1245: 100.00		ANR17_HUMAN (497-672): 1.36e-14: 81.6: 35.91
+	Hs
		348210 M4K4_HUMAN (1-1360): 0: 986: 59.18		TANC2_HUMAN (354-728): 8.24e-60: 229: 22.66
+	Rn
		1204182 Q5EB61_RAT (1005-1360): 2.85e-179: 536: 87.64		TANC1_RAT (590-969): 4.2e-72: 268: 30.69
+	Mm
		59045 TAOK2_MOUSE (1-858): 7.78e-132: 439: 22.25		TANC2_MOUSE (354-728): 1.18e-59: 228: 22.91
+	Hs
		1432025 TAOK2_HUMAN (1-861): 1.2e-130: 436: 22.29		TNKS2_HUMAN (250-584): 1.39e-51: 201: 15.95