Protein: TANC2
Protein TANC2 (Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2)

Gene: TANC2
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q9HCD6

Gene Ontology (top 5):
GO:0030424 - axon
GO:0043197 - dendritic spine
GO:0060998 - regulation of dendritic spine development
GO:0061001 - regulation of dendritic spine morphogenesis
GO:0099519 - dense core granule cytoskeletal transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1156218

ZYX
Zyxin

4

13

High-throughput

0.797

High

1438851

PAK5
Serine/threonine-protein kinase PAK 5

2

2

High-throughput

0.726

High

786862

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

5

3

High-throughput

0.712

High

1356647

IASPP
RelA-associated inhibitor

2

15

High-throughput

0.694

High

1116027

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.691

High

967984

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

3

High-throughput

0.667

High

1030698

ANK2
Ankyrin-2

1

18

High-throughput

0.618

High

1049008

REL
Proto-oncogene c-Rel

1

4

High-throughput

0.618

High

1116593

FHL3
Four and a half LIM domains protein 3

1

7

High-throughput

0.618

High

1399425

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

6

High-throughput

0.618

High

1438853

LIMD1
LIM domain-containing protein 1

1

10

High-throughput

0.618

High

1438857

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

5

High-throughput

0.618

High

1438847

KI13B
Kinesin-like protein KIF13B

1

4

High-throughput

0.618

High

730262

1433B
14-3-3 protein beta/alpha

3

20

High-throughput

0.593

High

966896

1433G
14-3-3 protein gamma

3

20

High-throughput

0.593

High

1049806

1433F
14-3-3 protein eta

3

20

High-throughput

0.593

High

1421264

RHG39
Rho GTPase-activating protein 39

3

5

High-throughput

0.593

High

1278931

BRAP
BRCA1-associated protein

1

4

Small-scale

0.587

High

972020

1433E
14-3-3 protein epsilon

3

5

High-throughput

0.578

High

255218

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.575

High

1396819

SNX27
Sorting nexin-27

2

16

High-throughput

0.558

High

269614

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

7

High-throughput

0.553

High

348210

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

14

High-throughput

0.553

High

765044

CTNB1
Catenin beta-1

1

6

High-throughput

0.553

High

955621

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.553

High

1216093

SPD2A
SH3 and PX domain-containing protein 2A

1

4

High-throughput

0.553

High

1255624

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

1352635

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

10

High-throughput

0.553

High

1438165

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.553

High

1438848

LATS2
Serine/threonine-protein kinase LATS2

1

2

High-throughput

0.553

High

1438850

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.553

High

1438855

ZBT21
Zinc finger and BTB domain-containing protein 21

1

3

High-throughput

0.553

High

167531

TX1B3
Tax1-binding protein 3

2

20

High-throughput

0.549

High

1438854

TNIK
TRAF2 and NCK-interacting protein kinase

1

13

High-throughput

0.528

High

691450

1433T
14-3-3 protein theta

2

20

High-throughput

0.521

High

245275

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.517

High

278164

FLNB
Filamin-B

1

17

High-throughput

0.489

High

637743

FLNA
Filamin-A

1

16

High-throughput

0.489

High

879487

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.489

High

1017494

FOXK1
Forkhead box protein K1

1

7

High-throughput

0.489

High

1029763

FOXK2
Forkhead box protein K2

1

7

High-throughput

0.489

High

1125405

FLNC
Filamin-C

1

18

High-throughput

0.489

High

1152255

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.489

High

1307526

RBM45
RNA-binding protein 45

1

4

High-throughput

0.489

High

1390301

TRI11
E3 ubiquitin-protein ligase TRIM11

1

4

High-throughput

0.489

High

1404420

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.489

High

1405995

C10
Protein C10

1

3

High-throughput

0.489

High

208736

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

2

High-throughput

0.479

High

637956

NF1
Neurofibromin

1

7

High-throughput

0.479

High

1227496

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.479

High

347346

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.445

High

106678

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

173396

XPO1
Exportin-1

1

9

High-throughput

0.437

High

252168

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

2

High-throughput

0.437

High

281424

GGYF1
GRB10-interacting GYF protein 1

1

9

High-throughput

0.437

High

404438

GCR
Glucocorticoid receptor

1

8

High-throughput

0.437

High

719374

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.437

High

730899

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

903259

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

1

High-throughput

0.437

High

984289

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

5

High-throughput

0.437

High

990760

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.437

High

1090187

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

10

High-throughput

0.437

High

1219622

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.437

High

1251444

GGYF2
GRB10-interacting GYF protein 2

1

14

High-throughput

0.437

High

1252239

SYNE3
Nesprin-3

1

20

High-throughput

0.437

High

1290160

THOC4
THO complex subunit 4

1

2

High-throughput

0.437

High

1293244

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

6

High-throughput

0.437

High

1309251

KSR1
Kinase suppressor of Ras 1

1

19

High-throughput

0.437

High

1346937

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.437

High

1352611

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.437

High

1389389

RNF31
E3 ubiquitin-protein ligase RNF31

1

6

High-throughput

0.437

High

1438849

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

1

High-throughput

0.437

High

1438852

CING
Cingulin

1

5

High-throughput

0.437

High

1438859

KCTD3
BTB/POZ domain-containing protein KCTD3

1

9

High-throughput

0.437

High

1258589

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

2

High-throughput

0.407

High

1288925

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

3

High-throughput

0.407

High

1400144

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

7

High-throughput

0.407

High

416768

TYSY
Thymidylate synthase

1

0

High-throughput

0.279

Low

1328595

RFLB
Refilin-B

1

0

High-throughput

0.279

Low

1389328

MOCOS
Molybdenum cofactor sulfurase

1

0

High-throughput

0.279

Low

1410847

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.249

Low

1412881

RTKN
Rhotekin

1

0

High-throughput

0.249

Low

1438856

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low

1438858

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025