HitPredict

Interactor 1: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Interactor 2: WASF2 (Q9Y6W5)
Actin-binding protein WASF2 (Protein WAVE-2) (Verprolin homology domain-containing protein 2) (Wiskott-Aldrich syndrome protein family member 2) (WASP family protein member 2)
Gene: WASF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1620 Hs			1 498
+	Hs
		323923 ALK_HUMAN (1-1620): 0: 1901: 100.00		SC31A_HUMAN (66-485): 3.01e-30: 127: 11.40
+	Hs
		1153523 ALK_HUMAN (1-1620): 0: 1901: 100.00		SPEG_HUMAN (160-460): 3.77e-26: 115: 17.09
+	Hs
		215959 ALK_HUMAN (1-1620): 0: 1901: 100.00		SYNJ1_HUMAN (41-458): 2.48e-09: 62: 10.54
+	Hs
		319116 ALK_HUMAN (1-1620): 0: 1901: 100.00		SC24D_HUMAN (222-408): 2.83e-09: 61.9: 20.32
+	Hs
		710926 EPHB2_HUMAN (938-1436): 1.28e-127: 427: 23.26		WASF2_HUMAN (1-498): 1.25e-64: 219: 100.00
+	Hs
		465704 IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77		WASF2_HUMAN (1-498): 1.25e-64: 219: 100.00
+	Hs
		710871 EPHB2_HUMAN (938-1436): 1.28e-127: 427: 23.26		WASF1_HUMAN (1-496): 8.94e-44: 164: 43.19
+	Hs
		323821 RET_HUMAN (804-1477): 5.87e-139: 460: 23.15		SC31A_HUMAN (66-485): 3.01e-30: 127: 11.40
+	Hs
		465591 IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77		WASF1_HUMAN (1-496): 8.94e-44: 164: 43.19
+	Hs
		179587 MUSK_HUMAN (983-1391): 1.78e-119: 399: 29.98		SC31A_HUMAN (66-485): 3.01e-30: 127: 11.40
+	Rn
		108114 INSR_RAT (973-1484): 1.46e-112: 392: 32.38		G3V699_RAT (66-485): 1.92e-29: 124: 12.08
+	Hs
		323822 IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77		SC31A_HUMAN (66-485): 3.01e-30: 127: 11.40
+	Rn
		92833 INSR_RAT (973-1484): 1.46e-112: 392: 32.38		D3ZAP7_RAT (97-472): 2.16e-26: 115: 10.00
+	Hs
		1145741 ERBB4_HUMAN (882-1541): 4.43e-121: 415: 22.42		TENS2_HUMAN (189-442): 9.13e-18: 88.9: 21.40
+	Rn
		98901 INSR_RAT (973-1484): 1.46e-112: 392: 32.38		F1M9G7_RAT (38-466): 6.82e-25: 111: 12.53
+	Rn
		580536 INSR_RAT (973-1484): 1.46e-112: 392: 32.38		SPEG_RAT (128-460): 5.33e-20: 96.2: 15.63
+	Mm
		582009 NTRK2_MOUSE (1093-1379): 6.23e-64: 236: 41.22		WASF1_MOUSE (1-496): 6.58e-43: 162: 43.19
+	Hs
		323818 NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07		SC31A_HUMAN (66-485): 3.01e-30: 127: 11.40
+	Hs
		411641 NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07		SC24C_HUMAN (121-418): 1.06e-12: 72.8: 15.36
+	Hs
		319083 NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07		SC24D_HUMAN (222-408): 2.83e-09: 61.9: 20.32