HitPredict

Interactor 1: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23752268
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Dicer_dimer, DEAD~Helicase_C, DEAD~Ribonuclease_3, Dicer_dimer~Ribonuclease_3, Dicer_dsRBD~Helicase_C, Dicer_dsRBD~Ribonuclease_3, Dicer_PBD~Dicer_PBD, Dicer_PBD~Helicase_C, Dicer_platform~PAZ, Dicer_platform~Ribonuclease_3, Helicase_C~Helicase_C, Helicase_C~Ribonuclease_3, PAZ~PAZ, PAZ~Ribonuclease_3, Ribonuclease_3~Ribonuclease_3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0004386 - helicase activity
GO:0004521 - RNA endonuclease activity
and 31 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1922
Hs

1 1922
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Hs
+ At
+ Mm
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ At

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Last updated: 11Aug2025