HitPredict

Interactor 1: HSP74 (Q9VG58)
Major heat shock 70 kDa protein Bbb (Heat shock protein 70Bbb) (HSP70-87C1)
Gene: Hsp70Bbb

Interactor 2: Q9XYW6 (Q9XYW6)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP)
Gene: STUB1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ANAPC3~HSP70
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 641 Dm			1 289
+	Dm
		1303883 HSP72_DROME (1-641): 0: 958: 99.84		Q9XYW6_DROME (1-289): 1.43e-57: 188: 100.00
+	Hs
		761538 HS71L_HUMAN (3-641): 0: 949: 74.22		CHIP_HUMAN (9-289): 2.79e-59: 192: 55.83
+	Dm
		1012157 HSP70_DROME (1-641): 0: 952: 98.13		Q9XYW6_DROME (1-289): 1.43e-57: 188: 100.00
+	Dm
		391860 HSP71_DROME (1-641): 0: 952: 98.13		Q9XYW6_DROME (1-289): 1.43e-57: 188: 100.00
+	Mm
		989295 HSP7C_MOUSE (2-641): 0: 938: 74.18		CHIP_MOUSE (9-289): 6.99e-60: 194: 55.83
+	Hs
		600961 HSP76_HUMAN (3-641): 0: 939: 71.09		CHIP_HUMAN (9-289): 2.79e-59: 192: 55.83
+	At
		1441395 HS704_ARATH (2-641): 0: 938: 68.94		CHIP_ARATH (14-288): 1.18e-49: 167: 32.73
+	Dm
		391841 HSP71_DROME (1-641): 0: 952: 98.13		Q9V3E9_DROME (9-237): 6.58e-30: 120: 18.80
+	Hs
		600777 HSP76_HUMAN (3-641): 0: 939: 71.09		PPP5_HUMAN (12-238): 8.85e-32: 124: 19.82
+	Mm
		989249 HSP7C_MOUSE (2-641): 0: 938: 74.18		PPP5_MOUSE (12-238): 5.87e-32: 125: 19.38
+	Hs
		536809 HSP7C_HUMAN (2-641): 0: 938: 74.18		PPP5_HUMAN (12-238): 8.85e-32: 124: 19.82
+	Hs
		1198774 Q53FA3_HUMAN (3-641): 0: 950: 74.22		DNJC7_HUMAN (18-211): 6.53e-24: 102: 19.60
+	Hs
		600938 HSP76_HUMAN (3-641): 0: 939: 71.09		RPAP3_HUMAN (6-157): 3e-27: 112: 23.03
+	Hs
		761494 HS71L_HUMAN (3-641): 0: 949: 74.22		DNJC7_HUMAN (18-211): 6.53e-24: 102: 19.60
+	Hs
		600911 HSP76_HUMAN (3-641): 0: 939: 71.09		DNJC7_HUMAN (18-211): 6.53e-24: 102: 19.60
+	At
		1441393 HS704_ARATH (2-641): 0: 938: 68.94		HSOP1_ARATH (21-200): 4.37e-21: 94.8: 15.71
+	Hs
		185383 HSP7C_HUMAN (2-641): 0: 938: 74.18		OGT1_HUMAN (4-235): 2.01e-15: 78.5: 10.92
+	Hs
		600897 HSP76_HUMAN (3-641): 0: 939: 71.09		SGTB_HUMAN (58-165): 1.2e-10: 63.1: 14.82
+	Hs
		226689 HSP7C_HUMAN (2-641): 0: 938: 74.18		SGTA_HUMAN (59-214): 1.43e-09: 59.6: 10.90
+	Mm
		989266 HSP7C_MOUSE (2-641): 0: 938: 74.18		SGTA_MOUSE (59-225): 3.15e-09: 58.9: 10.65