HitPredict

Interactor 1: DC1I1 (O14576)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: DYNC1I1

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005868 - cytoplasmic dynein complex
GO:0045503 - dynein light chain binding
GO:0045504 - dynein heavy chain binding
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 645
Hs

1 536
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Cr
+ Cr
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024