HitPredict

Interactor 1: RGS12 (O08774)
Regulator of G-protein signaling 12 (RGS12)
Gene: RGS12

Interactor 2: RASN (Q04970)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: Nras

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	17380122
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, RBD~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1387 Rn			1 189
+	Rn
		148255 RGS12_RAT (1-1387): 0: 1954: 100.00		RASH_RAT (16-188): 7.94e-79: 234: 83.82
+	Hs
		168027 RGS12_HUMAN (1-1384): 0: 1834: 83.69		RASH_HUMAN (16-188): 7.94e-79: 234: 83.82
+	Hs
		220431 RGS14_HUMAN (673-1242): 1.03e-177: 541: 38.62		RASH_HUMAN (16-188): 7.94e-79: 234: 83.82
+	Mm
		1021581 RGS14_MOUSE (673-1235): 1.54e-171: 524: 39.52		RAB35_MOUSE (4-171): 2.58e-84: 249: 34.71
+	Dm
		473626 Q9VCX2_DROME (573-1203): 2.98e-155: 502: 25.15		RAS1_DROME (1-170): 2.98e-90: 263: 83.53
+	Mm
		981393 RGS14_MOUSE (673-1235): 1.54e-171: 524: 39.52		RAB1A_MOUSE (4-185): 2.43e-74: 223: 33.70
+	Mm
		925772 RGS14_MOUSE (673-1235): 1.54e-171: 524: 39.52		RAB2A_MOUSE (4-185): 1.1e-73: 222: 31.52
+	Hs
		220443 RGS14_HUMAN (673-1242): 1.03e-177: 541: 38.62		RAP1A_HUMAN (1-165): 1.32e-60: 188: 56.29
+	Dm
		473571 Q9VCX2_DROME (573-1203): 2.98e-155: 502: 25.15		RAP1_DROME (1-163): 7.37e-63: 194: 59.15
+	Dm
		473625 RGS_DROME (9-442): 5.33e-114: 395: 30.53		RAS1_DROME (1-170): 2.98e-90: 263: 83.53
+	Dm
		473570 RGS_DROME (9-442): 5.33e-114: 395: 30.53		RAP1_DROME (1-163): 7.37e-63: 194: 59.15
+	Hs
		833401 RGS2_HUMAN (639-840): 7.93e-59: 203: 25.12		RAB2A_HUMAN (4-185): 1.8e-73: 221: 31.52
+	Hs
		833402 RGS2_HUMAN (639-840): 7.93e-59: 203: 25.12		RAP1B_HUMAN (1-165): 1.02e-61: 191: 56.89