Results from HitPredict v15 (11Aug2025 release)
Interactor 1: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6
Interactor 2: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.683 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23155421 |
| Identification Methods | tox-r dimerization assay, fluorescence technology, cosedimentation in solution |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~LRR_8, LRRCT~LRR_8, TIR~TIR |
| Common GO terms | GO:0001540 - amyloid-beta binding GO:0001774 - microglial cell activation GO:0002224 - toll-like receptor signaling pathway GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0004888 - transmembrane signaling receptor activity and 41 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025