HitPredict

Interactor 1: D6RAP2 (D6RAP2)
Toll like receptor 1
Gene: TLR1

Interactor 2: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LRR_8~LRR_8, LRRCT~LRR_8
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 161 Hs			1 796
+	Hs
		252377 TLR2_HUMAN (3-156): 2.37e-35: 131: 22.75		TLR6_HUMAN (1-796): 5.17e-133: 416: 100.00
+	Hs
		252351 TLR2_HUMAN (3-156): 2.37e-35: 131: 22.75		TLR1_HUMAN (12-791): 3.38e-128: 403: 68.16
+	Hs
		1417235 TLR10_HUMAN (2-151): 2.64e-10: 59.6: 16.35		TLR6_HUMAN (1-796): 5.17e-133: 416: 100.00
+	Hs
		1148235 TLR10_HUMAN (2-151): 2.64e-10: 59.6: 16.35		TLR1_HUMAN (12-791): 3.38e-128: 403: 68.16
+	At
		1442339 BRL2_ARATH (1-159): 7.43e-17: 78.4: 15.09		Y1571_ARATH (2-577): 1.97e-62: 229: 12.65
+	At
		88710 BRL2_ARATH (1-159): 7.43e-17: 78.4: 15.09		GSO1_ARATH (274-604): 1.24e-37: 154: 14.88
+	Hs
		252298 TLR2_HUMAN (3-156): 2.37e-35: 131: 22.75		TLR2_HUMAN (254-533): 4.07e-16: 84.9: 9.59
+	At
		1456492 BRL2_ARATH (1-159): 7.43e-17: 78.4: 15.09		Y1723_ARATH (216-681): 4.84e-32: 136: 12.95
+	Hs
		252372 TLR2_HUMAN (3-156): 2.37e-35: 131: 22.75		TLR10_HUMAN (5-285): 1.79e-10: 66.8: 13.59
+	Hs
		252310 PGS2_HUMAN (33-127): 2.81e-19: 84.6: 22.68		TLR2_HUMAN (254-533): 4.07e-16: 84.9: 9.59
+	At
		1491973 BRL2_ARATH (1-159): 7.43e-17: 78.4: 15.09		BRL2_ARATH (291-604): 1.56e-16: 86.5: 12.04
+	Hs
		252322 PGS1_HUMAN (1-159): 1.56e-17: 79.6: 17.65		TLR2_HUMAN (254-533): 4.07e-16: 84.9: 9.59
+	Hs
		252369 LGR4_HUMAN (46-157): 3.28e-16: 76.5: 22.61		TLR2_HUMAN (254-533): 4.07e-16: 84.9: 9.59
+	Zm
		19535 A0A1D6HD42_MAIZE (46-159): 9.8e-23: 95.4: 25.42		A0A1D6HD42_MAIZE (1-93): 1.19e-09: 64.1: 14.43
+	Hs
		317537 SLIT2_HUMAN (22-153): 8.78e-12: 63.8: 25.71		SLIT2_HUMAN (19-133): 1.85e-18: 92.9: 19.86
+	Hs
		126282 PGS2_HUMAN (33-127): 2.81e-19: 84.6: 22.68		TLR4_HUMAN (244-496): 3.18e-11: 69.2: 13.28
+	Hs
		126293 PGS1_HUMAN (1-159): 1.56e-17: 79.6: 17.65		TLR4_HUMAN (244-496): 3.18e-11: 69.2: 13.28
+	Hs
		126345 TLR6_HUMAN (45-153): 1.07e-09: 57.7: 23.89		TLR4_HUMAN (244-496): 3.18e-11: 69.2: 13.28
+	Hs
		1417231 TLR10_HUMAN (2-151): 2.64e-10: 59.6: 16.35		TLR10_HUMAN (5-285): 1.79e-10: 66.8: 13.59