Protein: TLR6
Toll-like receptor 6 (CD antigen CD286)

Gene: TLR6
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q9Y2C9

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0002224 - toll-like receptor signaling pathway
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1148239

TLR1
Toll-like receptor 1

3

15

Small-scale

0.843

High

252377

TLR2
Toll-like receptor 2

2

14

Small-scale

0.769

High

1490675

TLR6
Toll-like receptor 6

1

19

Small-scale

0.683

High

1054160

BTK
Tyrosine-protein kinase BTK

1

16

Small-scale

0.656

High

375028

RASH
GTPase HRas

1

8

Small-scale

0.647

High

126345

TLR4
Toll-like receptor 4

1

18

Small-scale

0.646

High

188607

SIGL5
Sialic acid-binding Ig-like lectin 5

1

20

Small-scale

0.618

High

1417235

TLR10
Toll-like receptor 10

1

15

Small-scale

0.590

High

598598

CD36
Platelet glycoprotein 4

1

1

Small-scale

0.536

High

94397

D6RAP2
Toll like receptor 1

1

19

High-throughput

0.514

High

1407684

MYD88
Myeloid differentiation primary response protein MyD88

1

20

Small-scale

0.506

High

331435

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

414883

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

139352

UPK2
Uroplakin-2

1

0

High-throughput

0.426

High

1090594

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

5

Small-scale

0.417

High

766030

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.407

High

1332383

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.328

High

351750

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025