HitPredict

Interactor 1: PMT3 (O13351)
Ubiquitin-like protein pmt3/smt3
Gene: PMT3

Interactor 2: NESP1 (O42980)
NEDD8-specific protease 1 (EC 3.4.22.-)
Gene: nep1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22730331
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Peptidase_C48~Rad60-SLD
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Sp			1 420
+	Sp
		149271 PMT3_SCHPO (1-117): 6.28e-54: 166: 100.00		ULP1_SCHPO (1-214): 1.89e-53: 188: 15.91
+	Hs
		939234 SUMO3_HUMAN (21-111): 3.29e-40: 130: 50.55		SENP1_HUMAN (2-215): 5.67e-66: 223: 16.37
+	Hs
		964480 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP1_HUMAN (2-215): 5.67e-66: 223: 16.37
+	Hs
		939232 SUMO3_HUMAN (21-111): 3.29e-40: 130: 50.55		SENP2_HUMAN (3-215): 3.78e-64: 217: 16.44
+	Xl
		1232932 SMO2B_XENLA (21-112): 7.83e-40: 129: 49.46		Q804S7_XENLA (2-215): 9.75e-64: 217: 15.93
+	Hs
		964462 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP2_HUMAN (3-215): 3.78e-64: 217: 16.44
+	Hs
		991434 SUMO1_HUMAN (9-111): 4.84e-36: 120: 48.54		SENP2_HUMAN (3-215): 3.78e-64: 217: 16.44
+	Sp
		149248 PMT3_SCHPO (1-117): 6.28e-54: 166: 100.00		ULP2_SCHPO (11-222): 2.13e-43: 162: 12.41
+	Xl
		1220127 SMO2B_XENLA (21-112): 7.83e-40: 129: 49.46		Q5XG28_XENLA (6-215): 3.65e-56: 193: 17.81
+	Hs
		964455 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP3_HUMAN (6-215): 2.03e-54: 191: 16.90
+	Dm
		356467 O97102_DROME (25-112): 5.36e-39: 127: 52.27		Q9VWK5_DROME (7-213): 1.44e-51: 188: 11.98
+	Xl
		82043 SMO2B_XENLA (21-112): 7.83e-40: 129: 49.46		B6RQN8_XENLA (6-215): 1.79e-51: 185: 16.36
+	Hs
		939223 SUMO3_HUMAN (21-111): 3.29e-40: 130: 50.55		SENP5_HUMAN (6-215): 1.27e-49: 181: 15.98
+	Hs
		964415 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP5_HUMAN (6-215): 1.27e-49: 181: 15.98
+	Hs
		964440 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP7_HUMAN (15-216): 1.29e-39: 153: 10.28
+	Xl
		84388 SMO2B_XENLA (21-112): 7.83e-40: 129: 49.46		B7TYL1_XENLA (13-118): 3.58e-24: 107: 14.88
+	Xl
		84389 SMO2B_XENLA (21-112): 7.83e-40: 129: 49.46		B7TYL2_XENLA (118-222): 2e-14: 77.5: 11.97
+	Mm
		1243152 SUMO3_MOUSE (21-112): 1.42e-41: 134: 50.00		SENP6_MOUSE (110-216): 4.49e-12: 70.2: 16.81
+	Hs
		964449 SUMO2_HUMAN (21-111): 1.15e-39: 129: 50.00		SENP6_HUMAN (110-216): 1.16e-11: 69: 16.81
+	Hs
		991421 SUMO1_HUMAN (9-111): 4.84e-36: 120: 48.54		SENP6_HUMAN (110-216): 1.16e-11: 69: 16.81