Interactor 1: IRS4 (O14654)
Insulin receptor substrate 4 (IRS-4) (160 kDa phosphotyrosine protein) (py160) (Phosphoprotein of 160 kDa) (pp160)
Gene: IRS4

Interactor 2: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 15316024
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005158 - insulin receptor binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008286 - insulin receptor signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1257
Hs

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Last updated: 15 Jul 2024