HitPredict

Interactor 1: ACT7 (P53492)
Actin-7 (EC 3.6.4.-) (Actin-2)
Gene: ACT7

Interactor 2: ADF6 (Q9ZSK2)
Actin-depolymerizing factor 6 (ADF-6) (AtADF6)
Gene: ADF6

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	21798944
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 At			1 146
+	At
		920974 ACT12_ARATH (1-377): 0: 749: 95.23		ADF6_ARATH (1-146): 1.39e-65: 197: 100.00
+	At
		1379620 ACT2_ARATH (1-377): 0: 738: 92.57		ADF3_ARATH (9-146): 1.58e-59: 182: 54.35
+	At
		920960 ACT11_ARATH (1-377): 0: 650: 95.76		ADF6_ARATH (1-146): 1.39e-65: 197: 100.00
+	Hs
		952697 ACTB_HUMAN (4-377): 0: 592: 89.84		DEST_HUMAN (12-145): 5.44e-47: 151: 30.26
+	Hs
		955834 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		DEST_HUMAN (12-145): 5.44e-47: 151: 30.26
+	Hs
		955818 ACTG_HUMAN (5-377): 0: 591: 90.08		DEST_HUMAN (12-145): 5.44e-47: 151: 30.26
+	Mm
		616470 ACTB_MOUSE (4-377): 0: 592: 89.84		COF1_MOUSE (12-145): 3.47e-46: 149: 30.07
+	Hs
		660017 ACTB_HUMAN (4-377): 0: 592: 89.84		COF1_HUMAN (12-145): 6.06e-46: 148: 30.07
+	Hs
		660081 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		COF1_HUMAN (12-145): 6.06e-46: 148: 30.07
+	Rn
		852477 ACTB_RAT (4-377): 0: 592: 89.84		COF1_RAT (12-145): 5.55e-46: 148: 30.07
+	Hs
		1168811 Q1KLZ0_HUMAN (4-377): 0: 592: 89.84		Q549N0_HUMAN (12-145): 1.39e-45: 147: 27.45
+	Hs
		660028 ACTG_HUMAN (5-377): 0: 591: 90.08		COF1_HUMAN (12-145): 6.06e-46: 148: 30.07
+	Hs
		952874 ACTB_HUMAN (4-377): 0: 592: 89.84		Q549N0_HUMAN (12-145): 1.39e-45: 147: 27.45
+	Hs
		953195 ACTB_HUMAN (4-377): 0: 592: 89.84		COF2_HUMAN (12-145): 1.39e-45: 147: 27.45
+	Hs
		952782 ACTB_HUMAN (4-377): 0: 592: 89.84		TWF1_HUMAN (13-145): 1.97e-36: 129: 25.71
+	Hs
		993148 ACTG_HUMAN (5-377): 0: 591: 90.08		TWF1_HUMAN (13-145): 1.97e-36: 129: 25.71
+	Hs
		952698 ACTB_HUMAN (4-377): 0: 592: 89.84		GMFB_HUMAN (17-145): 7.91e-38: 127: 21.81
+	Hs
		955875 ACTG_HUMAN (5-377): 0: 591: 90.08		GMFB_HUMAN (17-145): 7.91e-38: 127: 21.81
+	Ce
		534403 ACT4_CAEEL (4-377): 0: 593: 88.77		ADF1_CAEEL (12-142): 5.78e-31: 111: 29.22
+	Hs
		952893 ACTB_HUMAN (4-377): 0: 592: 89.84		TWF2_HUMAN (19-146): 2.46e-11: 61.9: 18.66