HitPredict

Interactor 1: TOR1B (O14657)
Torsin-1B (Torsin ATPase-1B) (EC 3.6.4.-) (Torsin family 1 member B)
Gene: TOR1B

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0016887 - ATP hydrolysis activity GO:0051085 - chaperone cofactor-dependent protein refolding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 336 Hs			1 654
+	Hs
		502188 TOR2A_HUMAN (45-336): 3.61e-114: 335: 44.52		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502558 TOR3A_HUMAN (1-336): 3.33e-112: 333: 35.65		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		503564 LONM_HUMAN (4-319): 5.02e-68: 231: 12.61		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502317 TOR2X_HUMAN (45-213): 1.43e-70: 221: 44.38		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		504728 CLPB_HUMAN (68-319): 1.31e-63: 215: 21.17		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		871771 CLPB_HUMAN (68-319): 1.31e-63: 215: 21.17		HSP72_HUMAN (25-636): 0: 905: 64.51
+	Pf
		1211398 Q8IIJ8_PLAF7 (66-310): 8.24e-65: 221: 18.92		Q8I2X4_PLAF7 (3-654): 0: 780: 65.04