HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: CRCM (P23508)
Colorectal mutant cancer protein (Protein MCC)
Gene: MCC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 19555689
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016055 - Wnt signaling pathway GO:0090090 - negative regulation of canonical Wnt signaling pathway
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 358 Hs			1 829
+	Hs
		1236743 USH1C_HUMAN (11-318): 9.95e-43: 157: 19.87		USBP1_HUMAN (232-811): 1.2e-86: 292: 25.80
+	Hs
		617559 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00
+	Hs
		617692 WHRN_HUMAN (4-306): 1.49e-43: 162: 21.61		CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00
+	Hs
		617545 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00
+	Hs
		617529 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00
+	Hs
		617632 SNX27_HUMAN (12-91): 4.35e-09: 59.7: 37.63		CRCM_HUMAN (1-829): 5.58e-54: 203: 100.00