HitPredict

Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 Hs			1 543
+	Hs
		154662 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		154661 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Sc
		579432 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPH_YEAST (2-542): 0: 587: 62.45
+	Hs
		154653 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Sc
		579430 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPE_YEAST (2-526): 0: 568: 29.98
+	Hs
		1202777 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Sc
		579422 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPG_YEAST (2-527): 0: 546: 30.68
+	Hs
		921038 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		1306704 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		826748 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		826604 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		573346 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821156 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		821437 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573204 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		821326 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		573384 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		843273 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843144 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79
+	Hs
		843411 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPD_HUMAN (24-520): 4.05e-90: 288: 33.79