HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 2240
+	Hs
		259627 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		YLPM1_HUMAN (1428-2236): 9.22e-43: 175: 14.56
+	Hs
		259864 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		BPTF_HUMAN (82-420): 1.92e-38: 161: 14.29
+	Hs
		259448 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		TCEA1_HUMAN (591-816): 6.26e-41: 155: 19.15
+	Hs
		260617 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		PHF8_HUMAN (236-386): 5.95e-24: 112: 23.31
+	Hs
		260233 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		PHF3_HUMAN (1933-2219): 8.09e-18: 93.2: 20.19
+	Hs
		260246 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		CBP_HUMAN (1049-1978): 2.17e-09: 65.4: 9.35
+	Hs
		259935 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		EIF3A_HUMAN (1921-2141): 4.61e-09: 64.3: 12.65
+	Hs
		1086767 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		BPTF_HUMAN (82-420): 1.92e-38: 161: 14.29
+	Hs
		674149 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		BPTF_HUMAN (82-420): 1.92e-38: 161: 14.29
+	Hs
		1141365 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		PHF8_HUMAN (236-386): 5.95e-24: 112: 23.31
+	Hs
		272827 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		PHF2_HUMAN (268-380): 1.14e-23: 112: 27.59
+	Hs
		272796 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		PHF2_HUMAN (268-380): 1.14e-23: 112: 27.59
+	Hs
		674271 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		TITIN_HUMAN (2-1275): 9.47e-22: 106: 10.12
+	Hs
		1141369 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		SRRM2_HUMAN (1059-2186): 1.18e-12: 76: 8.75
+	Hs
		1446407 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		CHD7_HUMAN (1473-1965): 9.84e-37: 155: 13.64
+	Hs
		1446440 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		PHF8_HUMAN (236-386): 5.95e-24: 112: 23.31
+	Pf
		1301930 Q8IB67_PLAF7 (336-462): 9.97e-26: 117: 26.77		Q8I5D0_PLAF7 (2050-2215): 7.47e-19: 96.8: 15.43
+	Hs
		1446444 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		SRRM2_HUMAN (1059-2186): 1.18e-12: 76: 8.75
+	Hs
		1121888 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		EIF3A_HUMAN (1921-2141): 4.61e-09: 64.3: 12.65
+	Hs
		1368446 KAT2B_HUMAN (327-456): 5.64e-22: 105: 26.92		CBP_HUMAN (1049-1978): 2.17e-09: 65.4: 9.35