HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: CIP2A (Q8TCG1)
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)
Gene: CIP2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25833693
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 905
+	Hs
		154959 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		DCTN1_HUMAN (546-889): 2.81e-19: 95.9: 9.97
+	Hs
		154901 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		HIP1R_HUMAN (691-884): 5.73e-09: 62: 15.20
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (391-893): 5.25e-21: 101: 14.50
+	Hs
		1137917 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MRCKA_HUMAN (391-893): 5.43e-19: 95.1: 13.94
+	Hs
		1137871 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKA_HUMAN (391-893): 5.43e-19: 95.1: 13.94
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (408-796): 4.1e-10: 66.2: 12.29
+	Rn
		361106 MYH6_RAT (190-583): 3.4e-15: 81.7: 10.63		MYH6_RAT (475-894): 1.43e-14: 80.9: 12.70
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (408-796): 4.1e-10: 66.2: 12.29
+	Hs
		522657 MYH4_HUMAN (185-613): 1.92e-14: 79.4: 9.46		MYH7_HUMAN (471-889): 5.54e-15: 82: 13.59
+	Hs
		528356 MYH6_HUMAN (243-632): 9.68e-15: 80.2: 14.50		MYH6_HUMAN (554-885): 1.12e-14: 80.9: 12.00
+	Hs
		255295 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		HIP1R_HUMAN (691-884): 5.73e-09: 62: 15.20
+	Hs
		1268126 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MRCKB_HUMAN (409-761): 2.16e-11: 70.1: 11.81
+	Hs
		528435 MYH4_HUMAN (185-613): 1.92e-14: 79.4: 9.46		MYH8_HUMAN (709-905): 6.46e-10: 65.5: 17.79
+	Hs
		502901 MYH6_HUMAN (243-632): 9.68e-15: 80.2: 14.50		MYH3_HUMAN (449-807): 2.03e-09: 63.9: 12.87
+	Hs
		502933 MYH4_HUMAN (185-613): 1.92e-14: 79.4: 9.46		MYH3_HUMAN (449-807): 2.03e-09: 63.9: 12.87
+	Hs
		528432 MYH13_HUMAN (264-631): 1.13e-12: 73.7: 10.83		MYH8_HUMAN (709-905): 6.46e-10: 65.5: 17.79