Interactor 1: GDF8 (O14793)
Growth/differentiation factor 8 (GDF-8) (Myostatin)
Gene: MSTN

Interactor 2: GDF11 (O95390)
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)
Gene: GDF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0005125 - cytokine activity
GO:0005615 - extracellular space
GO:0008083 - growth factor activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 375
Hs

1 407
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Last updated: 15 Jul 2024