HitPredict

Interactor 1: SOCS6 (O14544)
Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
Gene: SOCS6

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12052866
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 451
+	Hs
		156027 SOCS6_HUMAN (1-535): 0: 714: 100.00		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		557213 SRC_HUMAN (258-495): 1.88e-51: 185: 15.32		TBA4A_HUMAN (1-450): 0: 714: 96.00
+	Hs
		557212 SRC_HUMAN (258-495): 1.88e-51: 185: 15.32		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		439902 LCK_HUMAN (258-495): 2.35e-55: 195: 17.20		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		440022 LCK_HUMAN (258-495): 2.35e-55: 195: 17.20		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		463606 LYN_HUMAN (266-495): 8.96e-47: 172: 14.05		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		457199 SRC_HUMAN (258-495): 1.88e-51: 185: 15.32		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		594031 NCK1_HUMAN (188-466): 1.55e-46: 168: 15.46		TBA1A_HUMAN (1-451): 0: 710: 100.00
+	Hs
		457317 BLK_HUMAN (301-495): 1.88e-47: 174: 16.13		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		193178 SOCS1_HUMAN (379-535): 5.82e-42: 151: 26.75		TBB5_HUMAN (1-439): 0: 696: 40.77
+	Hs
		193251 SOCS1_HUMAN (379-535): 5.82e-42: 151: 26.75		TBB4B_HUMAN (1-437): 0: 694: 40.50
+	Hs
		136425 P85B_HUMAN (380-491): 1.9e-14: 78.2: 27.68		TBA1C_HUMAN (1-451): 0: 722: 98.00
+	Hs
		699692 P85A_HUMAN (384-496): 1.31e-12: 72.4: 23.89		TBA1B_HUMAN (1-440): 0: 712: 99.55
+	Hs
		136257 P85B_HUMAN (380-491): 1.9e-14: 78.2: 27.68		TBB5_HUMAN (1-439): 0: 696: 40.77