Interactor 1: IFIT3 (O14879)
Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (CIG49) (ISG-60) (Interferon-induced 60 kDa protein) (IFI-60K) (Interferon-induced protein with tetratricopeptide repeats 4) (IFIT-4) (Retinoic acid-induced gene G protein) (P60) (RIG-G)
Gene: IFIT3

Interactor 2: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 21813773
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~TPR_8
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009615 - response to virus
GO:0051607 - defense response to virus
GO:0140374 - antiviral innate immune response
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 490
Hs

1 925
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024