HitPredict

Interactor 1: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~Ank_2
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 1134
+	Mm
		1036444 ANK1_MOUSE (26-259): 8.21e-62: 211: 18.25		ANS1B_MOUSE (1-1133): 0: 594: 33.73
+	Mm
		109253 ANK3_MOUSE (29-259): 2.55e-65: 222: 19.85		ANK3_MOUSE (120-794): 5.97e-53: 206: 14.96
+	Hs
		158469 RFXK_HUMAN (1-260): 5.97e-85: 255: 100.00		ANKH1_HUMAN (2-106): 2.09e-14: 80.6: 24.76
+	Hs
		177209 ANK3_HUMAN (29-259): 1.24e-68: 231: 19.08		ANR28_HUMAN (246-510): 2.48e-21: 102: 11.60
+	Hs
		943984 RIPK4_HUMAN (61-259): 4.69e-44: 160: 20.50		MIB1_HUMAN (3-343): 1.55e-41: 168: 22.32
+	Hs
		1295554 Q9H4D1_HUMAN (61-259): 7.03e-44: 159: 20.50		MIB1_HUMAN (3-343): 1.55e-41: 168: 22.32
+	Hs
		1091461 ANK3_HUMAN (29-259): 1.24e-68: 231: 19.08		Q9H4D1_HUMAN (60-245): 4.6e-19: 95.1: 38.17
+	Mm
		109271 ANK3_MOUSE (29-259): 2.55e-65: 222: 19.85		ANK2_MOUSE (213-777): 2.32e-21: 103: 10.83
+	Hs
		943925 ANK3_HUMAN (29-259): 1.24e-68: 231: 19.08		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63
+	Hs
		177291 EHMT2_HUMAN (61-259): 1.09e-54: 191: 22.28		ANR28_HUMAN (246-510): 2.48e-21: 102: 11.60
+	Hs
		943916 RIPK4_HUMAN (61-259): 4.69e-44: 160: 20.50		ANK2_HUMAN (213-788): 7.76e-22: 105: 13.07
+	Hs
		1030692 Q9H4D1_HUMAN (61-259): 7.03e-44: 159: 20.50		ANK2_HUMAN (213-788): 7.76e-22: 105: 13.07
+	Hs
		1433495 ASB3_HUMAN (2-254): 7.86e-48: 167: 16.55		Q9H4D1_HUMAN (60-245): 4.6e-19: 95.1: 38.17
+	Hs
		944120 ASB3_HUMAN (2-254): 7.86e-48: 167: 16.55		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63
+	Hs
		1433435 Q9H4D1_HUMAN (61-259): 7.03e-44: 159: 20.50		Q9H4D1_HUMAN (60-245): 4.6e-19: 95.1: 38.17
+	Hs
		943889 RIPK4_HUMAN (61-259): 4.69e-44: 160: 20.50		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63
+	Hs
		1202610 ASB3_HUMAN (2-254): 7.86e-48: 167: 16.55		TNI3K_HUMAN (67-278): 8.66e-14: 78.2: 27.98
+	Mm
		1424412 RIPK4_MOUSE (61-259): 3.16e-43: 157: 20.00		RIPK4_MOUSE (62-289): 1.23e-13: 77.8: 32.61