HitPredict

Interactor 1: RFXK (O14593)
DNA-binding protein RFXANK (Ankyrin repeat family A protein 1) (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein)
Gene: RFXANK

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19465385
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042826 - histone deacetylase binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 488
+	Hs
		1368057 EHMT2_HUMAN (61-259): 1.09e-54: 191: 22.28		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1368129 EHMT1_HUMAN (3-171): 5.09e-47: 169: 16.47		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1109993 EHMT2_HUMAN (61-259): 1.09e-54: 191: 22.28		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		274215 ANR17_HUMAN (2-127): 2.17e-31: 124: 16.28		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1311358 ANKH1_HUMAN (2-123): 1.83e-29: 118: 13.82		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1110089 EHMT1_HUMAN (3-171): 5.09e-47: 169: 16.47		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		188368 ANRA2_HUMAN (34-252): 4.83e-73: 227: 57.27		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177211 ANR28_HUMAN (2-178): 9.21e-37: 139: 18.58		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		274143 ANR17_HUMAN (2-127): 2.17e-31: 124: 16.28		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		292311 TRPA1_HUMAN (89-242): 3.61e-13: 70.9: 28.21		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		1240215 RFXK_MOUSE (1-260): 5.36e-76: 233: 81.11		HDAC4_MOUSE (1-377): 6.15e-133: 412: 23.89
+	Mm
		59044 TANC2_MOUSE (5-179): 3.96e-13: 70.8: 13.71		HDAC4_MOUSE (1-377): 6.15e-133: 412: 23.89
+	Mm
		1240023 TNKS1_MOUSE (2-77): 2e-11: 65.8: 11.84		HDAC4_MOUSE (1-377): 6.15e-133: 412: 23.89