HitPredict

Interactor 1: UB2L6 (O14933)
Ubiquitin/ISG15-conjugating enzyme E2 L6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L6) (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6)
Gene: UBE2L6

Interactor 2: RN122 (Q9H9V4)
RING finger protein 122
Gene: RNF122

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 153 Hs			1 155
+	Hs
		159102 UB2L6_HUMAN (1-153): 2.2e-98: 281: 100.00		RN150_HUMAN (28-152): 1.27e-26: 105: 23.53
+	Hs
		1204871 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		GOLI_HUMAN (25-154): 3.75e-31: 117: 27.66
+	Hs
		849359 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		GOLI_HUMAN (25-154): 3.75e-31: 117: 27.66
+	Hs
		1356934 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RN150_HUMAN (28-152): 1.27e-26: 105: 23.53
+	Hs
		1148281 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RNF43_HUMAN (26-148): 1.56e-24: 100: 23.36
+	Hs
		849341 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		RNF43_HUMAN (26-148): 1.56e-24: 100: 23.36
+	Hs
		1262545 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		ZNRF4_HUMAN (16-146): 5.4e-24: 97.8: 22.86
+	Hs
		1332598 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RN167_HUMAN (24-137): 2.48e-24: 97.8: 24.79
+	Hs
		849385 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		ZNRF4_HUMAN (16-146): 5.4e-24: 97.8: 22.86
+	Hs
		1356614 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		AMFR_HUMAN (32-153): 3.08e-23: 96.3: 23.31
+	Hs
		849382 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		RN128_HUMAN (35-139): 1.33e-23: 96.7: 21.49
+	Hs
		1313520 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RN126_HUMAN (89-149): 1.21e-23: 95.5: 37.71
+	Hs
		849428 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		RN126_HUMAN (89-149): 1.21e-23: 95.5: 37.71
+	Hs
		207572 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RNF13_HUMAN (33-140): 8.45e-23: 94.4: 25.89
+	Hs
		207545 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		RNF13_HUMAN (33-140): 8.45e-23: 94.4: 25.89
+	Hs
		1377467 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RN115_HUMAN (83-147): 7.32e-23: 93.2: 35.39
+	Zm
		74334 B4FC97_MAIZE (2-149): 4.98e-76: 224: 36.24		B6U926_MAIZE (67-145): 6.76e-22: 91.7: 26.58
+	Zm
		79637 B6SZE0_MAIZE (2-149): 7.31e-76: 224: 35.57		B6U926_MAIZE (67-145): 6.76e-22: 91.7: 26.58
+	Hs
		1327690 UB2D4_HUMAN (2-149): 5.5e-76: 224: 38.93		RNF38_HUMAN (93-133): 4.57e-09: 55.8: 51.22
+	Hs
		849443 UB2D1_HUMAN (2-149): 1.04e-75: 223: 38.93		RNF38_HUMAN (93-133): 4.57e-09: 55.8: 51.22