HitPredict

Interactor 1: LCE2B (O14633)
Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B)
Gene: LCE2B

Interactor 2: KRA24 (Q9BYR9)
Keratin-associated protein 2-4 (High sulfur keratin-associated protein 2.4) (Keratin-associated protein 2.4)
Gene: KRTAP2-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 110 Hs			1 128
+	Hs
		159090 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA98_HUMAN (5-126): 1.95e-27: 100: 25.39
+	Hs
		159091 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA93_HUMAN (5-126): 9.31e-27: 99: 26.15
+	Hs
		159034 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA23_HUMAN (1-128): 5.61e-24: 90.9: 100.00
+	Hs
		159079 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA13_HUMAN (2-128): 4.31e-22: 87.5: 21.83
+	Hs
		159046 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR108_HUMAN (3-128): 2.68e-17: 76.7: 24.03
+	Hs
		159100 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA15_HUMAN (2-128): 9.83e-16: 70.9: 20.25
+	Hs
		159042 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR123_HUMAN (41-128): 7.93e-16: 69.3: 25.84
+	Hs
		159096 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA42_HUMAN (3-99): 2.58e-14: 66.3: 39.39
+	Hs
		159047 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR109_HUMAN (3-109): 1.14e-12: 64.7: 32.52
+	Hs
		159093 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR411_HUMAN (52-128): 1.93e-11: 60.1: 36.36
+	Hs
		159041 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR122_HUMAN (41-127): 1.52e-11: 59.3: 21.84
+	Hs
		159043 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR101_HUMAN (37-128): 6.61e-10: 57: 27.72
+	Hs
		159045 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR107_HUMAN (23-128): 7.23e-10: 57: 23.68
+	Hs
		159050 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA11_HUMAN (44-128): 2.16e-10: 57: 27.91
+	Hs
		159095 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA44_HUMAN (1-109): 7.57e-10: 55.5: 33.03
+	Hs
		159092 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KRA92_HUMAN (2-104): 1.17e-09: 55.1: 23.31
+	Hs
		159040 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR121_HUMAN (1-99): 6.82e-10: 53.9: 27.27
+	Hs
		159044 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR106_HUMAN (4-128): 9.41e-09: 53.9: 21.35
+	Hs
		159087 LCE2B_HUMAN (1-110): 8.41e-46: 145: 100.00		KR412_HUMAN (1-119): 9.77e-09: 52.8: 28.46