HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: NEK5 (Q6P3R8)
Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5)
Gene: NEK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34299191
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 708
+	Hs
		159719 DVL2_HUMAN (1-736): 0: 545: 100.00		MARK2_HUMAN (1-688): 7.08e-137: 423: 15.88
+	Hs
		159516 DVL2_HUMAN (1-736): 0: 545: 100.00		MARK3_HUMAN (1-665): 3.12e-135: 418: 16.60
+	Mm
		996597 DLG4_MOUSE (112-707): 3.19e-72: 251: 16.27		KAPCB_MOUSE (1-310): 1.02e-126: 381: 25.00
+	Dm
		94938 DLG1_DROME (13-707): 7.15e-51: 193: 14.03		E1JGN0_DROME (1-657): 7.91e-132: 419: 17.02
+	Hs
		936354 AFAD_HUMAN (256-712): 5.05e-48: 186: 21.41		MRCKA_HUMAN (2-631): 2.87e-130: 424: 19.17
+	Hs
		936370 AFAD_HUMAN (256-712): 5.05e-48: 186: 21.41		MARK2_HUMAN (1-688): 7.08e-137: 423: 15.88
+	Hs
		1270465 RIMS1_HUMAN (92-722): 1.81e-46: 181: 14.15		MARK2_HUMAN (1-688): 7.08e-137: 423: 15.88
+	Hs
		692020 AFAD_HUMAN (256-712): 5.05e-48: 186: 21.41		MARK3_HUMAN (1-665): 3.12e-135: 418: 16.60
+	Hs
		692090 RIMS1_HUMAN (92-722): 1.81e-46: 181: 14.15		MARK3_HUMAN (1-665): 3.12e-135: 418: 16.60
+	Hs
		1110269 RIMS1_HUMAN (92-722): 1.81e-46: 181: 14.15		KCC2B_HUMAN (2-550): 5.41e-131: 404: 17.81
+	Rn
		205625 NEB1_RAT (93-347): 3.9e-43: 170: 16.86		KS6B1_RAT (2-430): 4.93e-129: 394: 21.04
+	Dm
		900693 DSH_DROME (9-563): 2.98e-121: 378: 46.64		Q9W3N8_DROME (1-259): 5.01e-45: 174: 35.96
+	Hs
		692052 PTN13_HUMAN (94-534): 5.74e-17: 87.9: 15.42		MARK3_HUMAN (1-665): 3.12e-135: 418: 16.60