HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: PEF1 (Q9UBV8)
Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta-EF hand domain-containing protein 1)
Gene: PEF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 284
+	Hs
		1189525 ZFY16_HUMAN (137-497): 7.73e-39: 158: 17.76		PEF1_HUMAN (1-284): 2.65e-56: 184: 100.00
+	Hs
		241138 TOM1_HUMAN (5-428): 1.81e-54: 197: 18.16		CALM1_HUMAN (181-278): 2.7e-34: 123: 20.95
+	Hs
		241139 TOM1_HUMAN (5-428): 1.81e-54: 197: 18.16		CALM2_HUMAN (181-278): 2.7e-34: 123: 20.95
+	Hs
		241140 TOM1_HUMAN (5-428): 1.81e-54: 197: 18.16		CALM3_HUMAN (181-278): 2.7e-34: 123: 20.95
+	Hs
		483940 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		CALM1_HUMAN (181-278): 2.7e-34: 123: 20.95
+	Hs
		484015 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		CALM2_HUMAN (181-278): 2.7e-34: 123: 20.95
+	Hs
		484151 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		CALM3_HUMAN (181-278): 2.7e-34: 123: 20.95