HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: OTU7B (Q6GQQ9)
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Cezanne) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)
Gene: OTUD7B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	26446837, 29973362, 33669244
Identification Methods	enzymatic study, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 843
+	Hs
		160677 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		OTU7A_HUMAN (1-823): 0: 1135: 54.56
+	Hs
		160379 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		TNAP3_HUMAN (130-842): 5.32e-100: 330: 24.17
+	Hs
		160830 AURKA_HUMAN (1-403): 2.51e-162: 463: 100.00		ZRAN1_HUMAN (132-392): 2.26e-88: 297: 32.29
+	Hs
		599620 AKT1_HUMAN (27-401): 3.06e-138: 404: 25.07		TNAP3_HUMAN (130-842): 5.32e-100: 330: 24.17
+	Hs
		682057 AKT1_HUMAN (27-401): 3.06e-138: 404: 25.07		ZRAN1_HUMAN (132-392): 2.26e-88: 297: 32.29
+	Hs
		1292275 AURKB_HUMAN (126-395): 6.86e-131: 381: 71.43		ZRAN1_HUMAN (132-392): 2.26e-88: 297: 32.29