HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1030 Hs			1 779
+	Hs
		1206049 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		161388 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		167015 ANR28_HUMAN (1-175): 3.5e-38: 156: 20.99		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		161391 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		161387 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1331607 KDIS_HUMAN (1-162): 1.37e-32: 139: 19.10		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		161400 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		257697 ANR17_HUMAN (123-866): 2.56e-17: 89.9: 10.46		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		161453 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21
+	Hs
		556699 ANK1_HUMAN (1-934): 3.93e-69: 255: 12.47		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1167443 ANR50_HUMAN (22-935): 8.69e-65: 241: 13.09		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		299252 RIPK4_HUMAN (1-326): 1.53e-70: 253: 20.06		FARP2_HUMAN (5-183): 2.45e-30: 130: 21.69
+	Hs
		299289 Q9H4D1_HUMAN (1-326): 3.17e-70: 251: 20.06		FARP2_HUMAN (5-183): 2.45e-30: 130: 21.69
+	Hs
		883686 RIPK4_HUMAN (1-326): 1.53e-70: 253: 20.06		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		1330900 Q9H4D1_HUMAN (1-326): 3.17e-70: 251: 20.06		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		1206058 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1205980 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1167417 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1148963 PP12C_HUMAN (538-1030): 4.93e-33: 139: 20.35		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		1021392 ANK3_HUMAN (159-354): 1.67e-13: 77.6: 15.23		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28