HitPredict

Interactor 1: HNRDL (O14979)
Heterogeneous nuclear ribonucleoprotein D-like (hnRNP D-like) (hnRNP DL) (AU-rich element RNA-binding factor) (JKT41-binding protein) (Protein laAUF1)
Gene: HNRNPDL

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35256949, 24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 465
+	Hs
		226327 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226923 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226531 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227642 PAP1L_HUMAN (58-335): 3.92e-60: 207: 16.33		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227354 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227415 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		609949 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		161924 HNRDL_HUMAN (1-420): 1.19e-90: 282: 100.00		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		453681 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		RNF14_HUMAN (161-464): 6.69e-69: 229: 21.56
+	Hs
		1031383 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		312456 ROA1_HUMAN (136-317): 5.38e-82: 258: 36.17		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312523 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312478 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		312603 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Hs
		475505 ROA3_HUMAN (140-317): 8.69e-82: 257: 37.50		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475338 ROA2_HUMAN (139-356): 1.02e-75: 241: 34.51		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475708 PABP4_HUMAN (61-335): 1.63e-59: 206: 17.87		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475741 HNRPD_HUMAN (111-420): 3.55e-62: 206: 56.45		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		983451 PABP5_ARATH (143-327): 3.6e-32: 130: 14.82		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		186465 PABP4_ARATH (16-418): 1.89e-29: 122: 11.09		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17