HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: IFT81 (Q8WYA0)
Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)
Gene: IFT81

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	34079125, 26186194, 28514442, 33961781, unassigned3799
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 676
+	Hs
		163931 NDC80_HUMAN (1-642): 3.95e-79: 265: 100.00		DCTN1_HUMAN (253-630): 1.63e-33: 140: 15.26
+	Hs
		164105 NDC80_HUMAN (1-642): 3.95e-79: 265: 100.00		MYO5C_HUMAN (139-589): 1.83e-12: 73.1: 12.50
+	Hs
		1217577 MRCKB_HUMAN (310-642): 8.31e-19: 93.3: 12.39		MRCKA_HUMAN (153-673): 8.61e-39: 156: 13.04
+	Rn
		236530 MRCKB_RAT (310-642): 6.47e-18: 90.6: 12.13		MRCKA_RAT (153-673): 1.5e-39: 158: 12.67
+	Rn
		236526 MRCKA_RAT (336-642): 2.36e-17: 88.7: 10.17		MRCKA_RAT (153-673): 1.5e-39: 158: 12.67
+	Hs
		1217526 MRCKA_HUMAN (149-554): 5.83e-17: 87.5: 12.33		MRCKA_HUMAN (153-673): 8.61e-39: 156: 13.04
+	Hs
		773002 UACA_HUMAN (191-641): 1.52e-30: 130: 13.88		MYH9_HUMAN (212-673): 2.47e-20: 98.7: 9.52
+	Mm
		98073 MYH9_MOUSE (241-638): 2.92e-17: 88.7: 12.77		DESP_MOUSE (133-660): 1.76e-30: 130: 15.74
+	Mm
		98037 DESP_MOUSE (190-642): 1.19e-15: 83.5: 15.27		DESP_MOUSE (133-660): 1.76e-30: 130: 15.74
+	Hs
		773214 MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04		MYH14_HUMAN (131-643): 9.19e-29: 125: 17.52
+	Hs
		556892 MYH7_HUMAN (190-642): 2.72e-15: 82.1: 9.55		MYH7_HUMAN (17-661): 8.45e-22: 103: 9.46
+	Hs
		772645 MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04		MYH9_HUMAN (212-673): 2.47e-20: 98.7: 9.52
+	Hs
		773110 MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04		MYH10_HUMAN (13-555): 3.5e-20: 97.9: 7.92
+	Hs
		773112 MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04		MYH11_HUMAN (267-675): 2.43e-19: 95.2: 10.12
+	Hs
		556902 MYH7_HUMAN (190-642): 2.72e-15: 82.1: 9.55		MYH9_HUMAN (212-673): 2.47e-20: 98.7: 9.52
+	Rn
		1274668 MRCKB_RAT (310-642): 6.47e-18: 90.6: 12.13		MRCKB_RAT (94-566): 9.06e-17: 86.9: 14.03
+	Hs
		157021 MYH10_HUMAN (175-642): 1.34e-16: 86.3: 11.04		CTRO_HUMAN (108-651): 5.53e-15: 81.2: 15.41