HitPredict

Interactor 1: ARHGA (O15013)
Rho guanine nucleotide exchange factor 10
Gene: ARHGEF10

Interactor 2: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1369 Hs			1 802
+	Hs
		164095 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		164104 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		EPHA2_HUMAN (4-789): 0: 573: 19.58
+	Hs
		164126 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK2_HUMAN (114-757): 9.58e-166: 502: 25.84
+	Hs
		164125 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24
+	Hs
		164090 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		607984 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR4_HUMAN (13-802): 0: 750: 100.00
+	Hs
		607939 FGD1_HUMAN (69-982): 1.24e-90: 317: 14.59		FGFR4_HUMAN (13-802): 0: 750: 100.00
+	Hs
		508022 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		508143 ARHGQ_HUMAN (27-773): 6.23e-95: 328: 16.69		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		507829 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		FGFR1_HUMAN (3-794): 0: 706: 54.76
+	Hs
		609419 NGEF_HUMAN (171-774): 4.88e-89: 306: 16.48		FGFR3_HUMAN (5-799): 0: 712: 61.07
+	Hs
		385729 JIP3_HUMAN (776-1335): 1.15e-128: 432: 18.51		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		229615 JIP4_HUMAN (746-1338): 7.84e-125: 422: 15.88		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		665608 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		EPHB2_HUMAN (4-779): 0: 557: 17.27
+	Hs
		855777 VAV2_HUMAN (302-922): 4.52e-91: 317: 16.39		EPHA4_HUMAN (4-776): 0: 582: 19.47
+	Mm
		975148 NGEF_MOUSE (171-774): 2.4e-88: 305: 15.71		EPHA4_MOUSE (4-776): 0: 586: 19.47
+	Hs
		872675 NGEF_HUMAN (171-774): 4.88e-89: 306: 16.48		EPHA4_HUMAN (4-776): 0: 582: 19.47
+	Hs
		384538 VAV2_HUMAN (302-922): 4.52e-91: 317: 16.39		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		384821 ARHG7_HUMAN (288-972): 1.22e-91: 316: 12.61		NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53
+	Hs
		548695 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		MERTK_HUMAN (123-378): 2.1e-09: 63.2: 14.66