HitPredict

Interactor 1: ARHGA (O15013)
Rho guanine nucleotide exchange factor 10
Gene: ARHGEF10

Interactor 2: NTRK2 (Q16620)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (Tropomyosin-related kinase B)
Gene: NTRK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0022011 - myelination in peripheral nervous system
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1369 Hs			1 822
+	Hs
		164125 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK3_HUMAN (13-822): 1.98e-178: 536: 52.84
+	Hs
		164101 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68
+	Hs
		164090 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		164095 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		164104 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		EPHA2_HUMAN (148-822): 4.29e-141: 443: 22.43
+	Hs
		164118 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		ROR2_HUMAN (530-808): 1.44e-69: 249: 44.52
+	Hs
		164157 ARHGA_HUMAN (1-1369): 0: 1178: 100.00		ALK_HUMAN (513-799): 4.96e-64: 236: 41.44
+	Hs
		385729 JIP3_HUMAN (776-1335): 1.15e-128: 432: 18.51		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		229615 JIP4_HUMAN (746-1338): 7.84e-125: 422: 15.88		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		607984 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68
+	Hs
		508022 ITSN1_HUMAN (55-832): 2.19e-100: 356: 15.02		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		607939 FGD1_HUMAN (69-982): 1.24e-90: 317: 14.59		FGFR4_HUMAN (152-820): 3.01e-178: 534: 24.68
+	Hs
		384538 VAV2_HUMAN (302-922): 4.52e-91: 317: 16.39		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		384821 ARHG7_HUMAN (288-972): 1.22e-91: 316: 12.61		NTRK1_HUMAN (5-822): 2.36e-170: 513: 45.85
+	Hs
		508143 ARHGQ_HUMAN (27-773): 6.23e-95: 328: 16.69		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		507829 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		FGFR1_HUMAN (180-821): 3.75e-164: 498: 23.77
+	Hs
		1357274 JIP3_HUMAN (776-1335): 1.15e-128: 432: 18.51		ALK_HUMAN (513-799): 4.96e-64: 236: 41.44
+	Hs
		855789 VAV2_HUMAN (302-922): 4.52e-91: 317: 16.39		DDR1_HUMAN (535-807): 1.28e-74: 263: 47.37
+	Hs
		968455 ARHGQ_HUMAN (27-773): 6.23e-95: 328: 16.69		ROR2_HUMAN (530-808): 1.44e-69: 249: 44.52
+	Hs
		411288 VAV_HUMAN (297-904): 1.46e-90: 315: 15.35		INSR_HUMAN (513-809): 2.11e-70: 254: 43.38