Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 25315821, 34709727, 21653826
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~CUB, CUB~F5_F8_type_C, CUB~MAM, F5_F8_type_C~F5_F8_type_C, MAM~MAM
Common GO terms GO:0001525 - angiogenesis
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
GO:0001755 - neural crest cell migration
GO:0001764 - neuron migration
and 97 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 923
Hs

1 923
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Ss
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025