HitPredict

Interactor 1: SC16A (O15027)
Protein transport protein Sec16A (SEC16 homolog A) (p250)
Gene: SEC16A

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Sec16_C~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2357 Hs			1 342
+	Hs
		165042 SC16A_HUMAN (1-2357): 0: 820: 100.00		WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86
+	Hs
		164994 SC16A_HUMAN (1-2357): 0: 820: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Sc
		791177 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		PFS2_YEAST (78-327): 8.69e-79: 250: 25.69
+	Hs
		1309278 TARA_HUMAN (870-2322): 5.03e-09: 64.3: 9.42		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Sc
		817590 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		COPA_YEAST (131-323): 1.27e-23: 104: 16.81
+	Hs
		1302927 MINT_HUMAN (3-1242): 2.25e-12: 75.2: 13.32		NLE1_HUMAN (114-333): 2.06e-53: 184: 18.05
+	Hs
		1057782 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		1281391 PRR36_HUMAN (1219-2346): 2.98e-11: 71.6: 10.73		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903229 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Mm
		903669 KMT2C_MOUSE (1864-2326): 2.89e-11: 71.9: 12.13		WDR5_MOUSE (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		903374 KMT2C_HUMAN (1891-2314): 1.21e-10: 69.8: 14.58		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		302275 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79