HitPredict

Interactor 1: PER2 (O15055)
Period circadian protein homolog 2 (hPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: PER1 (O15534)
Period circadian protein homolog 1 (hPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui)
Gene: PER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 32296183, 33961781
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PAS_3~PAS_3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0001222 - transcription corepressor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1255
Hs

1 1290
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024