Interactor 1: PER2 (O15055)
Period circadian protein homolog 2 (hPER2) (Circadian clock protein PERIOD 2)
Gene: PER2

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.651

The method score is based on:

Property Details
Experiments 27834218, 25103245
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0002931 - response to ischemia
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1255
Hs

1 393
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024