Interactor 1: FYB1 (O15117)
FYN-binding protein 1 (Adhesion and degranulation promoting adaptor protein) (ADAP) (FYB-120/130) (p120/p130) (FYN-T-binding protein) (SLAP-130) (SLP-76-associated phosphoprotein)
Gene: FYB1

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 25814554, 9207119, 7504057, 9748251, 10229084, unassigned1126, 10409671, 17474147
Identification Methods two hybrid, affinity chromatography technology, pull down, validated two hybrid, two hybrid array, peptide array, coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH3_2, SH3_1~SH3_2
Common GO terms GO:0005102 - signaling receptor binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0050852 - T cell receptor signaling pathway
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 783
Hs

1 537
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Last updated: 15 Jul 2024