Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33144569
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001618 - virus receptor activity
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0045121 - membrane raft
GO:0048471 - perinuclear region of cytoplasm
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 798
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024