Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1
Interactor 2: NPC2 (P61916)
NPC intracellular cholesterol transporter 2 (Epididymal secretory protein E1) (Human epididymis-specific protein 1) (He1) (Niemann-Pick disease type C2 protein)
Gene: NPC2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.55 | 0.480 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27238017 |
| Identification Methods | isothermal titration calorimetry |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005576 - extracellular region GO:0005764 - lysosome GO:0005783 - endoplasmic reticulum GO:0008203 - cholesterol metabolic process GO:0010467 - gene expression and 7 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
