HitPredict

Interactor 1: SCAM2 (O15127)
Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2)
Gene: SCAMP2

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 329 Hs			1 216
+	Hs
		168500 SCAM2_HUMAN (1-329): 3.58e-156: 441: 100.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		168526 SCAM2_HUMAN (1-329): 3.58e-156: 441: 100.00		RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26
+	Hs
		168529 SCAM2_HUMAN (1-329): 3.58e-156: 441: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		168541 SCAM2_HUMAN (1-329): 3.58e-156: 441: 100.00		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		168358 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		168381 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18
+	Hs
		168446 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30
+	Hs
		168336 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		168373 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB5B_HUMAN (1-216): 1.1e-87: 259: 84.26
+	Hs
		168379 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		168431 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RAB1C_HUMAN (15-214): 6.14e-88: 259: 41.00
+	Hs
		168401 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		156476 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		156491 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18
+	Hs
		725 A0A087WXB0_HUMAN (1-314): 2.34e-125: 363: 50.48		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		156456 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		728 A0A087WXB0_HUMAN (1-314): 2.34e-125: 363: 50.48		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		156489 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		156506 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89
+	Hs
		1079951 SCAM4_HUMAN (116-329): 3.53e-82: 250: 45.12		RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89