Interactor 1: IMA6 (O15131)
Importin subunit alpha-6 (Karyopherin subunit alpha-5)
Gene: KPNA5

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Arm, Arm~Arm_3, Arm~IBB, Arm_3~IBB
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
GO:0006607 - NLS-bearing protein import into nucleus
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 539
Hs

1 538
+ Hs
+ Hs
+ Mm
+ Sp
+ Sc
+ Sp
+ Dm

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Last updated: 15 Jul 2024