HitPredict

Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 36380368
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 2647
+	Hs
		597996 LIS1_HUMAN (1-232): 1.28e-57: 194: 13.49		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598268 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598040 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598209 WDR5B_HUMAN (178-369): 5.06e-47: 164: 18.56		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598300 KTNB1_HUMAN (129-363): 2.42e-44: 163: 13.45		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		282821 CIAO1_HUMAN (142-357): 1.52e-27: 112: 17.78		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		261236 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		FLNB_HUMAN (28-2647): 0: 2710: 69.63
+	Hs
		598025 SEC13_HUMAN (20-297): 6.9e-23: 99.5: 20.46		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598345 NLE1_HUMAN (1-79): 6.06e-21: 95.9: 18.99		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		598240 POC1B_HUMAN (1-82): 9.12e-21: 95.2: 10.98		FLNA_HUMAN (1-2647): 0: 2776: 100.00
+	Hs
		211635 ARC1A_HUMAN (1-371): 6.17e-84: 261: 67.83		ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01
+	Hs
		168685 ARC1B_HUMAN (9-372): 1.2e-79: 250: 100.00		ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01
+	Hs
		903137 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62
+	Hs
		46280 A0A1W2PNV4_HUMAN (204-358): 8.15e-10: 62.5: 8.08		ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01
+	Hs
		957556 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		PGBM_HUMAN (181-1251): 3.53e-32: 140: 12.81