Protein: ZFYV9
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)

Gene: ZFYV9, ZFYVE9
Organism: Homo sapiens
Interactions: 109
UniProt ID: O95405

Gene Ontology (top 5):
GO:0005545 - 1-phosphatidylinositol binding
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006897 - endocytosis
GO:0007179 - transforming growth factor beta receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

336107

SMAD2
Mothers against decapentaplegic homolog 2

11

12

Small-scale

0.981

High

336092

SMAD3
Mothers against decapentaplegic homolog 3

10

12

Small-scale

0.978

High

336076

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

8

12

High-throughput

0.753

High

336086

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

12

Small-scale

0.738

High

336147

RNF11
RING finger protein 11

3

5

Small-scale

0.685

High

336072

PML
Protein PML

3

12

Small-scale

0.640

High

296411

STAM2
Signal transducing adapter molecule 2

1

20

Small-scale

0.618

High

336100

SMAD4
Mothers against decapentaplegic homolog 4

1

12

Small-scale

0.618

High

336104

EEA1
Early endosome antigen 1

1

18

High-throughput

0.618

High

336119

ZFY16
Zinc finger FYVE domain-containing protein 16

1

14

Small-scale

0.618

High

336141

ANFY1
Rabankyrin-5

1

10

High-throughput

0.618

High

336140

SPN90
NCK-interacting protein with SH3 domain

2

0

High-throughput

0.602

High

336054

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

16

Small-scale

0.595

High

336081

RAB9A
Ras-related protein Rab-9A

2

20

High-throughput

0.584

High

336051

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.515

High

336053

OPSD
Rhodopsin

1

4

Small-scale

0.512

High

336099

STX3
Syntaxin-3

1

11

Small-scale

0.512

High

291162

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.508

High

336060

PLAK
Junction plakoglobin

1

6

High-throughput

0.508

High

336073

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

High-throughput

0.508

High

336075

CTNB1
Catenin beta-1

1

5

High-throughput

0.508

High

336077

BAG6
Large proline-rich protein BAG6

1

10

High-throughput

0.508

High

336087

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

12

High-throughput

0.508

High

336098

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

5

High-throughput

0.508

High

336102

FHL2
Four and a half LIM domains protein 2

1

3

High-throughput

0.508

High

336103

DAZP2
DAZ-associated protein 2

1

2

High-throughput

0.508

High

336113

UBX11
UBX domain-containing protein 11

1

1

High-throughput

0.508

High

336120

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

6

High-throughput

0.508

High

336125

SPART
Spartin

1

10

High-throughput

0.508

High

336135

AMPB
Aminopeptidase B

1

4

High-throughput

0.508

High

336143

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

6

High-throughput

0.508

High

336148

LRP12
Low-density lipoprotein receptor-related protein 12

1

3

Small-scale

0.506

High

336093

CLH1
Clathrin heavy chain 1

1

8

Small-scale

0.501

High

336061

ETS2
Protein C-ets-2

1

0

High-throughput

0.486

High

189362

STX7
Syntaxin-7

1

10

High-throughput

0.479

High

225897

STX6
Syntaxin-6

1

8

High-throughput

0.479

High

299000

FLOT1
Flotillin-1

1

6

High-throughput

0.479

High

336047

HERC2
E3 ubiquitin-protein ligase HERC2

1

11

High-throughput

0.479

High

336048

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

336049

FOS
Protein c-Fos

1

3

High-throughput

0.479

High

336050

RASK
GTPase KRas

1

18

High-throughput

0.479

High

336052

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

20

High-throughput

0.479

High

336055

LAMP1
Lysosome-associated membrane glycoprotein 1

1

15

High-throughput

0.479

High

336056

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

336058

IFM1
Interferon-induced transmembrane protein 1

1

12

High-throughput

0.479

High

336059

LAMP2
Lysosome-associated membrane glycoprotein 2

1

15

High-throughput

0.479

High

336062

AMPN
Aminopeptidase N

1

4

High-throughput

0.479

High

336063

PGFRA
Platelet-derived growth factor receptor alpha

1

20

High-throughput

0.479

High

336064

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

336065

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

336066

RAB4A
Ras-related protein Rab-4A

1

17

High-throughput

0.479

High

336067

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.479

High

336078

VASP
Vasodilator-stimulated phosphoprotein

1

1

High-throughput

0.479

High

336079

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.479

High

336080

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.479

High

336082

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

336083

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

336084

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.479

High

336085

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

336088

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

336089

RB11A
Ras-related protein Rab-11A

1

7

High-throughput

0.479

High

336090

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

336091

CXAR
Coxsackievirus and adenovirus receptor

1

10

High-throughput

0.479

High

336094

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

336096

IFM3
Interferon-induced transmembrane protein 3

1

12

High-throughput

0.479

High

336097

CAV1
Caveolin-1

1

5

High-throughput

0.479

High

336101

CUL3
Cullin-3

1

15

High-throughput

0.479

High

336105

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

336108

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

336109

OCLN
Occludin

1

2

High-throughput

0.479

High

336115

LTOR1
Ragulator complex protein LAMTOR1

1

9

High-throughput

0.479

High

336118

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

336132

TS101
Tumor susceptibility gene 101 protein

1

4

Small-scale

0.479

High

336133

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

336134

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

8

Small-scale

0.479

High

336136

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

336137

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

336142

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

336144

MYO6
Unconventional myosin-VI

1

13

High-throughput

0.479

High

336145

LAMP3
Lysosome-associated membrane glycoprotein 3

1

15

High-throughput

0.479

High

130342

SPT5H
Transcription elongation factor SPT5

1

3

High-throughput

0.464

High

336112

SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

1

4

High-throughput

0.464

High

336117

SCYL2
SCY1-like protein 2

1

4

High-throughput

0.464

High

336122

NIT1
Deaminated glutathione amidase

1

1

High-throughput

0.464

High

336124

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.464

High

336128

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

4

High-throughput

0.464

High

336131

ERBIN
Erbin

1

4

High-throughput

0.464

High

336139

CAH10
Carbonic anhydrase-related protein 10

1

1

High-throughput

0.445

High

336130

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.439

High

217659

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.437

High

336068

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.437

High

336069

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

336071

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.437

High

336106

EPHA7
Ephrin type-A receptor 7

1

18

High-throughput

0.437

High

336110

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

1

High-throughput

0.437

High

336111

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.437

High

336116

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.437

High

336121

TM11B
Transmembrane protease serine 11B

1

4

High-throughput

0.437

High

336126

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.437

High

336146

R3HD2
R3H domain-containing protein 2

1

6

High-throughput

0.437

High

336114

Q5TF85
polynucleotide adenylyltransferase

1

1

High-throughput

0.417

High

336095

DEF6
Defensin-6

2

0

High-throughput

0.328

High

336138

ST7
Suppressor of tumorigenicity 7 protein

1

0

Small-scale

0.288

High

336057

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.265

Low

336123

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.265

Low

336127

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

0

High-throughput

0.265

Low

336070

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

336074

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

336129

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025