HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: EPN3 (Q9H201)
Epsin-3 (EPS-15-interacting protein 3)
Gene: EPN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.634

Property	Details
Experiments	26186194, 28514442, 32296183, 33961781
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 632
+	Hs
		111205 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		I6L9I8_HUMAN (1-316): 1.19e-106: 326: 94.30
+	Hs
		1328942 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		EPN3_HUMAN (1-632): 1.32e-92: 300: 100.00
+	Hs
		175627 TRI18_HUMAN (1-667): 1.27e-180: 530: 100.00		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		307570 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		1057061 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		EPN4_HUMAN (3-628): 4.33e-76: 256: 21.77
+	Hs
		307538 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		1172486 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		EPN1_HUMAN (1-592): 3.16e-57: 204: 37.64
+	Hs
		1049027 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		EPN4_HUMAN (3-628): 4.33e-76: 256: 21.77
+	Hs
		787934 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		EPS15_HUMAN (38-569): 4e-46: 177: 10.26
+	Hs
		161678 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		GAK_HUMAN (173-548): 3.67e-40: 159: 16.46
+	Hs
		867105 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		SC24C_HUMAN (287-632): 3.11e-12: 72.1: 12.00
+	Hs
		203236 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		SYNJ1_HUMAN (291-630): 4.09e-11: 68.5: 12.15
+	Hs
		1170060 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		SRCAP_HUMAN (307-630): 4.91e-09: 62: 12.09
+	Hs
		307561 TRI62_HUMAN (89-339): 7.42e-27: 116: 16.08		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		307511 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		EPN2_HUMAN (1-632): 5.11e-66: 229: 33.54
+	Hs
		1170080 TRI54_HUMAN (1-380): 7.45e-80: 259: 22.80		SRCAP_HUMAN (307-630): 4.91e-09: 62: 12.09
+	Hs
		734550 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		EPS15_HUMAN (38-569): 4e-46: 177: 10.26