HitPredict

Interactor 1: BIRC5 (O15392)
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
Gene: BIRC5

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.626

The method score is based on:

Property Details
Experiments 21988832, 27332895
Identification Methods two hybrid, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005819 - spindle
GO:0005876 - spindle microtubule
and 5 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 142
Hs

1 309
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024