Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 11741539, 33961781, 26186194, 28514442, 29568061, 24981860, 20603326, 26655834, 20404198, unassigned3799
Identification Methods biochemical, affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~WD40
Common GO terms GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
and 4 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 372
Hs

1 418
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Service provided by Combinatics, Japan

Last updated: 11Aug2025