HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: KLF6 (Q99612)
Krueppel-like factor 6 (B-cell-derived protein 1) (Core promoter element-binding protein) (GC-rich sites-binding factor GBF) (Proto-oncogene BCD1) (Suppressor of tumorigenicity 12 protein) (Transcription factor Zf9)
Gene: KLF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 283
+	Hs
		180832 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZNF74_HUMAN (4-259): 2.78e-97: 300: 14.65
+	Hs
		180873 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN383_HUMAN (4-203): 1.21e-76: 242: 8.92
+	Hs
		180930 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN287_HUMAN (4-151): 4.92e-48: 172: 6.96
+	Hs
		180640 TIF1A_HUMAN (1-1050): 0: 584: 100.00		KLF8_HUMAN (93-282): 1.61e-50: 171: 44.85
+	Hs
		180810 TIF1A_HUMAN (1-1050): 0: 584: 100.00		KLF5_HUMAN (137-282): 1.13e-46: 164: 52.06
+	Hs
		180760 TIF1A_HUMAN (1-1050): 0: 584: 100.00		KLF3_HUMAN (141-283): 2.55e-47: 162: 52.67
+	Hs
		180847 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZFP1_HUMAN (124-282): 4.91e-42: 150: 20.00
+	Hs
		180635 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN254_HUMAN (2-150): 6.89e-39: 145: 9.43
+	Hs
		180795 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN543_HUMAN (4-136): 4.49e-32: 126: 6.99
+	Hs
		180955 TIF1A_HUMAN (1-1050): 0: 584: 100.00		KLF15_HUMAN (198-282): 3.36e-32: 124: 62.35
+	Hs
		180623 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN264_HUMAN (4-136): 2.03e-30: 121: 8.39
+	Hs
		180704 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZNF10_HUMAN (35-254): 5.01e-19: 88.6: 12.34
+	Hs
		180865 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN695_HUMAN (202-283): 8.83e-14: 72.8: 28.05
+	Hs
		67043 TIF1A_HUMAN (1-1050): 0: 584: 100.00		ZN726_HUMAN (2-70): 6.8e-12: 67.5: 8.33
+	Hs
		339896 TRI33_HUMAN (52-1045): 5.84e-145: 464: 46.71		KLF8_HUMAN (93-282): 1.61e-50: 171: 44.85
+	Hs
		1241447 TRI33_HUMAN (52-1045): 5.84e-145: 464: 46.71		ZFP1_HUMAN (124-282): 4.91e-42: 150: 20.00
+	Hs
		464832 PML_HUMAN (7-627): 1.07e-65: 240: 17.00		SP1_HUMAN (103-282): 1.44e-57: 198: 33.18
+	Hs
		600391 TRIM1_HUMAN (31-473): 9.88e-72: 255: 14.68		ZNF24_HUMAN (11-282): 6.86e-54: 180: 22.38
+	Hs
		714041 PML_HUMAN (7-627): 1.07e-65: 240: 17.00		SP2_HUMAN (143-283): 1.79e-49: 174: 40.43
+	Hs
		714075 PML_HUMAN (7-627): 1.07e-65: 240: 17.00		KLF10_HUMAN (196-283): 2.42e-30: 120: 68.18