Protein: SP2
Transcription factor Sp2

Gene: SP2
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q02086

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1034870

FHL2
Four and a half LIM domains protein 2

4

10

High-throughput

0.704

High

1034878

BANP
Protein BANP

4

5

High-throughput

0.703

High

1034869

NFYC
Nuclear transcription factor Y subunit gamma

3

8

High-throughput

0.653

High

464916

SP1
Transcription factor Sp1

1

18

High-throughput

0.646

High

1034887

KLF15
Krueppel-like factor 15

1

16

High-throughput

0.618

High

1034874

NRF1
Nuclear respiratory factor 1

2

2

High-throughput

0.606

High

1029057

E2F1
Transcription factor E2F1

1

10

Small-scale

0.561

High

1034875

QRIC1
Transcriptional regulator QRICH1

2

15

High-throughput

0.553

High

756154

MCM7
DNA replication licensing factor MCM7

1

0

High-throughput

0.549

High

872220

SOX2
Transcription factor SOX-2

1

19

High-throughput

0.536

High

1034867

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.536

High

1034888

UBQL1
Ubiquilin-1

1

10

High-throughput

0.515

High

915433

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.513

High

1034877

ZDH17
Palmitoyltransferase ZDHHC17

1

16

High-throughput

0.494

High

630253

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

8

High-throughput

0.489

High

1034880

VWCE
von Willebrand factor C and EGF domain-containing protein

1

20

High-throughput

0.489

High

1034883

NKX31
Homeobox protein Nkx-3.1

1

15

Small-scale

0.481

High

142947

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

395941

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

473925

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

533920

IRF1
Interferon regulatory factor 1

1

1

Small-scale

0.479

High

549311

SRF
Serum response factor

1

8

High-throughput

0.479

High

714041

PML
Protein PML

1

20

High-throughput

0.479

High

837036

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.479

High

878981

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

979522

H4
Histone H4

1

5

High-throughput

0.479

High

1034868

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1034871

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1034872

EEA1
Early endosome antigen 1

1

7

High-throughput

0.479

High

1034873

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

20

Small-scale

0.479

High

1034879

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.479

High

1034881

FEV
Protein FEV

1

20

High-throughput

0.479

High

1034882

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1034885

RC3H2
Roquin-2

1

17

High-throughput

0.479

High

442296

GELS
Gelsolin

1

3

High-throughput

0.470

High

650132

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.470

High

1034876

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

421948

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.457

High

293584

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

1034886

HECW2
E3 ubiquitin-protein ligase HECW2

1

9

High-throughput

0.437

High

1034884

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.316

High

49309

SHOT1
Shootin-1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025