Protein: S39A4
Zinc transporter ZIP4 (Solute carrier family 39 member 4) (Zrt- and Irt-like protein 4) (ZIP-4)

Gene: S39A4, SLC39A4
Organism: Homo sapiens
Interactions: 164
UniProt ID: Q6P5W5

Gene Ontology (top 5):
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006882 - intracellular zinc ion homeostasis
GO:0008270 - zinc ion binding
GO:0016324 - apical plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

254343

ATP9A
Probable phospholipid-transporting ATPase IIA

3

2

High-throughput

0.667

High

302723

SLIK5
SLIT and NTRK-like protein 5

3

2

High-throughput

0.667

High

305507

ZFPL1
Zinc finger protein-like 1

3

4

High-throughput

0.667

High

311090

MPZL1
Myelin protein zero-like protein 1

3

4

High-throughput

0.667

High

567118

CXA1
Gap junction alpha-1 protein

3

11

High-throughput

0.667

High

570545

PTN2
Tyrosine-protein phosphatase non-receptor type 2

3

7

High-throughput

0.667

High

573752

PTN1
Tyrosine-protein phosphatase non-receptor type 1

3

7

High-throughput

0.667

High

957860

EFNB1
Ephrin-B1

3

2

High-throughput

0.667

High

990502

CKAP4
Cytoskeleton-associated protein 4

3

7

High-throughput

0.667

High

1160130

LRP10
Low-density lipoprotein receptor-related protein 10

3

3

High-throughput

0.667

High

1160140

ABD12
Lysophosphatidylserine lipase ABHD12

3

1

High-throughput

0.667

High

1160143

GOLM1
Golgi membrane protein 1

3

2

High-throughput

0.667

High

1160157

EDA
Ectodysplasin-A

3

1

High-throughput

0.667

High

1160158

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

3

2

High-throughput

0.667

High

1160167

S47A1
Multidrug and toxin extrusion protein 1

3

1

High-throughput

0.667

High

1160180

TACAN
Ion channel TACAN

3

1

High-throughput

0.667

High

1160189

S1PR5
Sphingosine 1-phosphate receptor 5

3

20

High-throughput

0.667

High

1160192

FKRP
Ribitol 5-phosphate transferase FKRP

3

1

High-throughput

0.667

High

1160195

AT132
Polyamine-transporting ATPase 13A2

3

2

High-throughput

0.667

High

1160210

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

1

High-throughput

0.667

High

172582

GNPAT
Dihydroxyacetone phosphate acyltransferase

3

0

High-throughput

0.638

High

200745

ADCY6
Adenylate cyclase type 6

3

0

High-throughput

0.638

High

619249

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

0

High-throughput

0.638

High

792905

SATT
Neutral amino acid transporter A

3

0

High-throughput

0.638

High

830084

MA2A2
Alpha-mannosidase 2x

3

0

High-throughput

0.638

High

1132936

CSCL2
CSC1-like protein 2

3

0

High-throughput

0.638

High

1145549

STEA3
Metalloreductase STEAP3

3

0

High-throughput

0.638

High

1156765

MFS12
Major facilitator superfamily domain-containing protein 12

3

0

High-throughput

0.638

High

1160141

CISD2
CDGSH iron-sulfur domain-containing protein 2

3

0

High-throughput

0.638

High

1160144

SIDT2
SID1 transmembrane family member 2

3

0

High-throughput

0.638

High

1160165

OMA1
Metalloendopeptidase OMA1, mitochondrial

3

0

High-throughput

0.638

High

1160177

NDC1
Nucleoporin NDC1

3

0

High-throughput

0.638

High

254173

FZD7
Frizzled-7

2

4

High-throughput

0.628

High

161536

S27A2
Long-chain fatty acid transport protein 2

2

2

High-throughput

0.611

High

217175

EXTL3
Exostosin-like 3

2

5

High-throughput

0.611

High

392691

B3A2
Anion exchange protein 2

2

1

High-throughput

0.611

High

1053369

FZD2
Frizzled-2

2

4

High-throughput

0.611

High

1160134

CHSS1
Chondroitin sulfate synthase 1

2

7

High-throughput

0.611

High

1160136

LRC8A
Volume-regulated anion channel subunit LRRC8A

2

1

High-throughput

0.611

High

1160196

GPC5C
G-protein coupled receptor family C group 5 member C

2

1

High-throughput

0.611

High

49333

T120B
Transmembrane protein 120B

3

1

High-throughput

0.609

High

129395

GOLI4
Golgi integral membrane protein 4

3

4

High-throughput

0.609

High

238874

TPST2
Protein-tyrosine sulfotransferase 2

3

1

High-throughput

0.609

High

708108

ABCD1
ATP-binding cassette sub-family D member 1

3

4

High-throughput

0.609

High

795026

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

998420

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

3

2

High-throughput

0.609

High

1016077

SRBP2
Sterol regulatory element-binding protein 2

3

1

High-throughput

0.609

High

1158665

LTMD1
LETM1 domain-containing protein 1

3

1

High-throughput

0.609

High

1160135

GLBL2
Beta-galactosidase-1-like protein 2

3

1

High-throughput

0.609

High

1160149

LEMD2
LEM domain-containing protein 2

3

2

High-throughput

0.609

High

1160150

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

3

2

High-throughput

0.609

High

1160168

FACR2
Fatty acyl-CoA reductase 2

3

1

High-throughput

0.609

High

1160179

CA043
Protein C1orf43

3

1

High-throughput

0.609

High

1160185

5NT3A
Cytosolic 5'-nucleotidase 3A

3

1

High-throughput

0.609

High

1160187

METL9
Protein-L-histidine N-pros-methyltransferase

3

2

High-throughput

0.609

High

1160199

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

3

2

High-throughput

0.609

High

764654

CUX1
Homeobox protein cut-like 1

3

9

High-throughput

0.599

High

1160147

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.585

High

1160176

TMM43
Transmembrane protein 43

2

0

High-throughput

0.585

High

1160182

LNP
Endoplasmic reticulum junction formation protein lunapark

2

0

High-throughput

0.585

High

474495

GPHRB
Golgi pH regulator B

3

3

High-throughput

0.585

High

1160205

ELOV2
Very long chain fatty acid elongase 2

2

6

High-throughput

0.574

High

657372

ABCD3
ATP-binding cassette sub-family D member 3

2

5

High-throughput

0.558

High

1120168

GPAT3
Glycerol-3-phosphate acyltransferase 3

2

5

High-throughput

0.558

High

1158711

CC033
Protein C3orf33

2

3

High-throughput

0.558

High

1160175

PGAP4
Post-GPI attachment to proteins factor 4

2

2

High-throughput

0.558

High

1160183

ELOV4
Very long chain fatty acid elongase 4

2

6

High-throughput

0.558

High

1160200

VPS45
Vacuolar protein sorting-associated protein 45

2

2

High-throughput

0.558

High

1160204

RMND1
Required for meiotic nuclear division protein 1 homolog

2

1

High-throughput

0.558

High

429072

ADRB2
Beta-2 adrenergic receptor

1

9

High-throughput

0.541

High

156849

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.536

High

183380

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

2

High-throughput

0.536

High

212885

STX6
Syntaxin-6

1

4

High-throughput

0.536

High

295733

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

3

High-throughput

0.536

High

311862

TRI16
Tripartite motif-containing protein 16

1

1

High-throughput

0.536

High

328345

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.536

High

598743

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.536

High

600778

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

9

High-throughput

0.536

High

782432

P2RY2
P2Y purinoceptor 2

1

19

High-throughput

0.536

High

783658

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

3

High-throughput

0.536

High

958360

AT8B2
Phospholipid-transporting ATPase ID

1

3

High-throughput

0.536

High

1030972

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

19

High-throughput

0.536

High

1133818

AGRF1
Adhesion G-protein coupled receptor F1

1

2

High-throughput

0.536

High

1158492

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.536

High

1160125

S27A1
Long-chain fatty acid transport protein 1

1

2

High-throughput

0.536

High

1160128

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

5

High-throughput

0.536

High

1160129

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.536

High

1160133

P2RY8
P2Y purinoceptor 8

1

20

High-throughput

0.536

High

1160152

SPP2B
Signal peptide peptidase-like 2B

1

5

High-throughput

0.536

High

1160159

T106A
Transmembrane protein 106A

1

2

High-throughput

0.536

High

1160163

S22AI
Solute carrier family 22 member 18

1

9

High-throughput

0.536

High

1160164

APH1A
Gamma-secretase subunit APH-1A

1

1

High-throughput

0.536

High

1160174

CIB1
Calcium and integrin-binding protein 1

1

2

High-throughput

0.536

High

1160191

AT133
Polyamine-transporting ATPase 13A3

1

2

High-throughput

0.536

High

1160193

LPAR2
Lysophosphatidic acid receptor 2

1

18

High-throughput

0.536

High

1160202

GP173
Probable G-protein coupled receptor 173

1

14

High-throughput

0.536

High

1160203

T106B
Transmembrane protein 106B

1

2

High-throughput

0.536

High

1160213

GPR45
Probable G-protein coupled receptor 45

1

14

High-throughput

0.536

High

156518

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.513

High

1160138

AN13A
Ankyrin repeat domain-containing protein 13A

1

0

High-throughput

0.513

High

1160146

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

1160156

PIEZ1
Piezo-type mechanosensitive ion channel component 1

1

0

High-throughput

0.513

High

1160172

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.513

High

1160184

T126A
Transmembrane protein 126A

1

0

High-throughput

0.513

High

1160186

MAGT1
Magnesium transporter protein 1

1

0

High-throughput

0.513

High

1160197

DUOX1
Dual oxidase 1

1

0

High-throughput

0.513

High

81816

GPHRA
Golgi pH regulator A

2

3

High-throughput

0.504

High

1047391

CASP
Protein CASP

2

10

High-throughput

0.504

High

152160

STX16
Syntaxin-16

1

8

High-throughput

0.489

High

157592

MGST3
Glutathione S-transferase 3, mitochondrial

1

1

High-throughput

0.489

High

235183

STX10
Syntaxin-10

1

4

High-throughput

0.489

High

646610

AOFB
Amine oxidase [flavin-containing] B

1

1

High-throughput

0.489

High

1053743

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

1

2

High-throughput

0.489

High

1147548

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.489

High

1160132

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

6

High-throughput

0.489

High

1160139

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

1

High-throughput

0.489

High

1160153

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.489

High

1160160

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

1

1

High-throughput

0.489

High

1160169

MBOA7
Lysophospholipid acyltransferase 7

1

2

High-throughput

0.489

High

1160173

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.489

High

1160188

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.489

High

1160209

EXTL2
Exostosin-like 2

1

5

High-throughput

0.489

High

1160212

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.489

High

526511

GP1BB
Platelet glycoprotein Ib beta chain

1

5

High-throughput

0.479

High

1160170

PCFT
Proton-coupled folate transporter

1

8

High-throughput

0.479

High

1160207

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.479

High

173480

RER1
Protein RER1

1

0

High-throughput

0.458

High

1032780

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

0

High-throughput

0.458

High

214773

PM34
Peroxisomal membrane protein PMP34

1

3

High-throughput

0.437

High

643229

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

1

High-throughput

0.437

High

1110235

S2552
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A52

1

4

High-throughput

0.437

High

1131281

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

2

High-throughput

0.437

High

1160126

DHR13
Dehydrogenase/reductase SDR family member 13

1

1

High-throughput

0.437

High

1160151

GOGA5
Golgin subfamily A member 5

1

7

High-throughput

0.437

High

1160155

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

2

High-throughput

0.437

High

1160194

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

1

High-throughput

0.437

High

1160201

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

1

3

High-throughput

0.437

High

1124763

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

3

0

High-throughput

0.347

High

1160127

HACD2
Very-long-chain

3

0

High-throughput

0.347

High

1160131

PIGW
Phosphatidylinositol-glycan biosynthesis class W protein

3

0

High-throughput

0.347

High

1160148

UXS1
UDP-glucuronic acid decarboxylase 1

3

0

High-throughput

0.347

High

1160161

TM143
Transmembrane protein 143

3

0

High-throughput

0.347

High

1160162

TM186
Transmembrane protein 186

3

0

High-throughput

0.347

High

1160181

FUT8
Alpha-(1,6)-fucosyltransferase

3

0

High-throughput

0.347

High

433063

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

0

High-throughput

0.328

High

1160142

FITM2
Acyl-coenzyme A diphosphatase FITM2

2

0

High-throughput

0.328

High

1160137

TM192
Transmembrane protein 192

2

0

High-throughput

0.318

High

1160178

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

2

0

High-throughput

0.318

High

1160206

SELN
Selenoprotein N

2

0

High-throughput

0.318

High

131806

FAAH1
Fatty-acid amide hydrolase 1

1

0

High-throughput

0.279

Low

152435

EI24
Etoposide-induced protein 2.4 homolog

1

0

High-throughput

0.279

Low

514406

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

1130882

TM201
Transmembrane protein 201

1

0

High-throughput

0.279

Low

1160145

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.279

Low

1160154

PIGO
GPI ethanolamine phosphate transferase 3

1

0

High-throughput

0.279

Low

1160166

T3HPD
Trans-3-hydroxy-L-proline dehydratase

1

0

High-throughput

0.279

Low

1160171

PIGS
GPI transamidase component PIG-S

1

0

High-throughput

0.279

Low

1160190

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.279

Low

1160208

TM181
Transmembrane protein 181

1

0

High-throughput

0.279

Low

1160211

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.279

Low

212214

ERD23
ER lumen protein-retaining receptor 3

1

0

High-throughput

0.249

Low

875993

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

1120714

ORML2
ORM1-like protein 2

1

0

High-throughput

0.249

Low

1160198

AAAS
Aladin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024