HitPredict

Interactor 1: STX7 (O15400)
Syntaxin-7
Gene: STX7

Interactor 2: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.969

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311, 30833792, 9417091, 40437099, unassigned3799
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	SNAP~SNARE
Common GO terms	GO:0000149 - SNARE binding GO:0006886 - intracellular protein transport GO:0019905 - syntaxin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Hs			1 295
+	Hs
		189828 STX7_HUMAN (1-261): 9.29e-70: 217: 100.00		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Mm
		204935 STX1A_MOUSE (7-259): 3.2e-65: 206: 24.90		SNAA_MOUSE (1-295): 2.19e-113: 330: 98.31
+	Hs
		746223 STX2_HUMAN (7-256): 2.05e-65: 207: 27.13		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Rn
		746106 STX1A_RAT (7-259): 2.78e-65: 206: 24.90		SNAA_RAT (1-295): 8.47e-113: 329: 98.31
+	Hs
		933012 STX1A_HUMAN (6-259): 6.07e-65: 205: 24.05		SNAA_HUMAN (1-295): 2.14e-113: 330: 100.00
+	Hs
		1159633 STX1A_HUMAN (6-259): 6.07e-65: 205: 24.05		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Hs
		960354 STX1B_HUMAN (7-258): 2.13e-64: 204: 22.31		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Hs
		933028 STX12_HUMAN (10-244): 3.43e-58: 188: 54.01		SNAA_HUMAN (1-295): 2.14e-113: 330: 100.00
+	Hs
		1294829 STX12_HUMAN (10-244): 3.43e-58: 188: 54.01		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Dm
		1171600 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		SNAP_DROME (5-295): 7.88e-105: 308: 61.51
+	Hs
		933004 STX3_HUMAN (4-237): 2.82e-52: 173: 23.33		SNAA_HUMAN (1-295): 2.14e-113: 330: 100.00
+	Hs
		1100716 STX3_HUMAN (4-237): 2.82e-52: 173: 23.33		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	Hs
		1430777 X5D7S1_HUMAN (6-258): 7.78e-53: 173: 22.05		SNAB_HUMAN (1-292): 6.05e-113: 329: 84.25
+	At
		1020618 SYP22_ARATH (3-245): 3.88e-59: 190: 29.63		SNAA2_ARATH (12-291): 2.6e-91: 274: 41.64
+	At
		1184743 SYP21_ARATH (4-245): 2.27e-55: 180: 32.25		SNAA2_ARATH (12-291): 2.6e-91: 274: 41.64
+	Hs
		189796 STX7_HUMAN (1-261): 9.29e-70: 217: 100.00		SNAG_HUMAN (4-265): 6.78e-68: 215: 23.40
+	Hs
		1294817 STX12_HUMAN (10-244): 3.43e-58: 188: 54.01		SNAG_HUMAN (4-265): 6.78e-68: 215: 23.40
+	Dm
		1174532 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		Q9U6R9_DROME (4-265): 3.86e-58: 190: 18.49
+	Hs
		1100712 STX3_HUMAN (4-237): 2.82e-52: 173: 23.33		SNAG_HUMAN (4-265): 6.78e-68: 215: 23.40
+	Dm
		1174540 STX1A_DROME (1-256): 1.06e-63: 202: 22.73		Q9VH25_DROME (18-265): 1.81e-53: 177: 17.53